IP Library Granted Patent US 9,207,159
Granted Patent B2
US 9,207,159 · App. 13/326,188 · Granted Dec 8, 2015

Particle analyzer for analyzing particles

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Quick Facts
Patent No.
US 9,207,159
App. No.
13/326,188
Granted
Dec 8, 2015
Kind
B2
Abstract

A particle analyzer may include a sampling unit configured to collect samples containing particles; a sample preparing unit configured to prepare different sub-samples; a reaction unit configured to incubate the sub-samples and one or more corresponding reagents respectively and provide them to the injecting unit; an injecting unit configured to inject the sub-samples to the optical unit; an optical unit configured to irradiate the sub-samples to obtain particle information; a processing unit configured to process and output the particle information; and a threshold value unit configured to compare a total number of particles with a pre-determined threshold value and to output a result of the comparison to the injecting unit to control subsequent injection of one or more sub-samples.

Claims (21)

1. A particle analyzer comprising:

a sampling unit;

a sample preparing unit;

an optical unit configured;

an injecting unit;

a reaction unit;

a processing unit; and

a computer readable medium with encoded computer-executable instructions that, when executed by the processing unit, cause the processing unit to perform operations for outputting the particle information for an injection cycle, the operations comprising:

instructing the sampling unit to collect samples containing particles;

instructing the sample preparing unit to prepare a plurality of sub-samples;

instructing the reaction unit to incubate the particles and one or more corresponding reagents;

instructing the injecting unit to inject a first sub-sample having a first preset volume and a first number of particles to the optical unit;

instructing the optical unit to irradiate the injected particles to obtain particle information associated with the particles;

comparing the first number of particles with a pre-determined threshold value;

outputting a result of the comparison to the injecting unit; and

controlling a volume of a subsequent, second injection of at least a second sub-sample based on the result of the comparison, wherein the volume of the second injection is different than a second preset volume of the second sub-sample.

2. The particle analyzer according to claim 1 , wherein the sample preparing unit of the particle analyzer is configured to prepare sub-samples for total particle counting and particle classification.

3. The particle analyzer according to claim 2 , wherein the injecting unit injects a sub-sample for total particle counting in a pre-determined volume and injects a sub-sample for particle classification according to a result of comparing the number of particles of the sub-sample with a threshold value, and when a number of the particles is not less than the threshold value, the injecting unit injects the sub-sample in a first injecting volume, and when a number of the particles is less than the threshold value, the injecting unit injects the sub-sample in a second injecting volume, the first injecting volume being less than the second injecting volume.

4. The particle analyzer according to claim 3 , wherein the injecting unit employs a motor to drive the injecting unit to inject the sub-sample in the first injecting volume or the second injecting volume by controlling a speed and/or driving time of the motor.

5. The particle analyzer according to claim 1 , wherein the samples are blood samples and the particles are white blood cells.

6. The particle analyzer according to claim 1 , wherein the processing unit outputs scatter diagrams.

Assignments (4)
LICENSE Recorded Jun 24, 2022
From: SHENZHEN MINDRAY BIOMEDICAL ELECTRONICS CO., LTD.
To: SHENZHEN MINDRAY ANIMAL MEDICAL TECHNOLOGY CO., LTD.
Reel/Frame 060440/0796 →
ASSIGNMENT OF FIFTY PERCENT (50%) OF THE ASSIGNOR ENTIRE RIGHT Recorded Nov 18, 2019
From: SHENZHEN MINDRAY SCIENTIFIC CO., LTD.
To: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
Reel/Frame 051050/0276 →
ASSIGNMENT OF 50% OF THE ASSIGNOR ENTIRE RIGHT Recorded Jul 25, 2018
From: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
To: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.; SHENZHEN MINDRAY SCIENTIFIC CO., LTD.
Reel/Frame 046624/0546 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 15, 2011
From: GUO, WENHENG; TENG, JIN; ZHAN, YINGJIAN; ZHOU, SHUANG; SHI, HUILIN
To: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD
Reel/Frame 027395/0073 →