Intra-surgical optical coherence tomographic imaging of cataract procedures
A cataract surgical system includes a laser source to generate a first set of laser pulses; a guiding optic to guide the first set of laser pulses to a cataract target region in an eye; a laser controller to generate an electronic representation of a target scan pattern, and to control the guiding optic to scan the first set of laser pulses according to a portion of the target scan pattern to create a first photo-disrupted region in the cataract target region; and a Spectral Domain Optical Coherence Tomographic (SD-OCT) imaging system to generate an image of a portion of the first photo-disrupted region. The laser controller can generate an electronic representation of a modified scan pattern in relation to the image generated by the SD-OCT imaging system, and control the guiding optic to scan a second set of laser pulses according the modified scan pattern.
1. A cataract surgical system, comprising:
a laser source, configured to generate a first set of laser pulses;
a guiding optic, coupled to the laser source, configured to guide the first set of laser pulses to a cataract target region in an eye;
a laser controller, configured
to generate an electronic representation of a target scan pattern, and
to control the guiding optic to scan the first set of laser pulses according to a portion of the target scan pattern to create a first photo-disrupted region in the cataract target region; and
a Spectral Domain Optical Coherence Tomographic (SD-OCT) imaging system, configured to generate an image that includes a portion of the first photo-disrupted region with an image resolution in the range of 0.5-5 million image points per image and a frame-rate in the range of 20-200 frames/sec; wherein
the laser controller is configured
to generate an electronic representation of a modified scan pattern in relation to the image generated by the SD-OCT imaging system, and
to control the guiding optic to scan a second set of laser pulses according the modified scan pattern to create a second photo-disrupted region.
2. The cataract surgical system of claim 1 , wherein:
the cataract target region comprises an anterior capsular layer; and
the target scan pattern comprises a set of target points on a cylinder to form at least one of a circular capsulotomy, an anterior capsulotomy, and a curvilinear capsulotomy.
3. The cataract surgical system of claim 1 , wherein:
the cataract target region comprises a portion of the lens; and
the target scan pattern comprises a set of target points on at least one of radial chop planes, cylinders, a spiral pattern and a mesh pattern to induce at least one of a chop, a photo-disruption and a lysis of the lens.
4. The cataract surgical system of claim 1 , wherein:
the SD-OCT imaging system is configured to have a z-imaging range greater than 4 mm.
5. The cataract surgical system of claim 1 , wherein:
the SD-OCT imaging system is configured to have a z-imaging range greater than 6 mm.
6. The cataract surgical system of claim 1 , wherein:
the SD-OCT imaging system does not generate the image of the portion of the first photo-disrupted region by integrating two or more images with imaging ranges less than 4 mm.
7. The cataract surgical system of claim 1 , wherein:
the SD-OCT imaging system is configured to generate the image in an imaging time less than 1 sec.
8. The cataract surgical system of claim 1 , wherein:
the SD-OCT imaging system is configured to generate the image in an imaging time less than 0.1 sec.
9. The cataract surgical system of claim 1 , wherein:
the SD-OCT imaging system is configured to generate repeated images with a frame-rate in the range of 25-500 frames/sec.
10. The cataract surgical system of claim 1 , wherein:
the SD-OCT imaging system is configured to generate repeated images with an (x,y) resolution in the range of 500-2,000 A-scans per B-scan.
11. The cataract surgical system of claim 1 , wherein:
the SD-OCT imaging system is configured to generate repeated images with an (x,y) resolution in the range of 2,000-5,000 A-scans per B-scan.
12. The cataract surgical system of claim 1 , wherein:
the SD-OCT imaging system is configured to generate repeated images with an image resolution in the range of 0.5-2 million image points per image.
13. The cataract surgical system of claim 1 , wherein:
the SD-OCT imaging system is configured to generate repeated images with an image resolution in the range of 2-5 million image points per image.
14. The cataract surgical system of claim 1 , wherein:
the SD-OCT imaging system is configured to generate a B-scan from A-scans comprising image points from at least 1000 z-depths.
15. The cataract surgical system of claim 1 , wherein:
the SD-OCT imaging system is configured to generate repeated images with a refresh rate in the range of 1-10 frames/sec with a high image resolution in the range of 2-5 million image points.
16. The cataract surgical system of claim 1 , wherein:
the laser controller is configured to generate the electronic representation of the modified target scan pattern according to a modification input received from the system operator in response to the system operator having analyzed the image of the portion of the first photo-disrupted region.
17. The cataract surgical laser system of claim 1 , wherein:
the SD-OCT imaging system is configured to display calibration marks to assist the system operator to calibrate a location of the first photo-disrupted region relative to the target scan pattern.
18. The cataract surgical system of claim 1 , wherein:
the SD-OCT imaging system includes a Spectrometer-Based-OCT imaging system, comprising:
a broad-band light source to generate a broad-band beam;
a beam guidance system
to split the broad-band beam into an image beam and a reference beam,
to guide the image beam to the eye and to guide a returned image beam from the eye,
to guide the reference beam to a reference mirror and to guide a returned reference beam from the reference mirror, and
to combine the returned image beam and the returned reference beam into a combined beam; and
an OCT camera, configured to receive the combined beam, comprising
a spectral decomposer to decompose the combined beam into spectral components;
a sensor array to sense the spectral components;
a Fast-Fourier-Transformer system to generate a Fourier transform from the sensed spectral components; and
an image generator, to generate an image from the Fourier transformed spectral components.
19. The cataract surgical system of claim 18 , the SD-OCT imaging system comprising:
a dedicated Input-Output board configured to output target scan pattern control signals, wherein
the dedicated Input-Output board comprises
a dedicated memory controller
a data buffer; and
an output Digital-Analog Converter; and
the imaging by the SD-OCT imaging system is synchronized with the outputting of the target scan pattern control signals by the output Digital-Analog Converter.
20. A cataract surgical system, comprising:
a laser source, configured to generate a first set of laser pulses;
a guiding optic, coupled to the laser source, configured to guide the first set of laser pulses to a lens of an eye;
a laser controller, configured
to generate an electronic representation of a target scan pattern, and
to control the guiding optic to scan the first set of laser pulses according to the target scan pattern to create a first photo-disrupted region; and
a Swept-Source Optical Coherence Tomographic (SS-OCT) imaging system, configured to generate an image of a portion of the first photo-disrupted region with an image resolution in the range of 0.5-5 million image points per image and a frame-rate in the range of 20-200 frames/sec; wherein
the laser controller is configured
to generate an electronic representation of a modified scan pattern in relation to the image generated by the SS-OCT imaging system, and
to control the guiding optic to scan a second set of laser pulses according the modified scan pattern to create a second photo-disrupted region.
21. The cataract surgical system of claim 20 , the Swept-Source-OCT imaging system comprising:
a swept wavelength light source to generate a swept-wavelength beam;
a beam guidance system, configured
to split the swept-wavelength beam into an image beam and a reference beam,
to guide the image beam to the eye and to guide a returned image beam from the eye,
to guide the reference beam to a reference mirror and to guide a returned reference beam from the reference mirror, and
to combine the returned image beam and the returned reference beam into a combined beam; and
an OCT camera, configured to receive the combined beam, comprising
a detector to detect the combined beam;
a data binner to detect the combined beam as a time sequence of data;
a Fast-Fourier-Transform-system to Fourier transform the detected time sequence of data; and
an image generator to generate an image from the Fourier transform.
22. A cataract surgical system, comprising:
a surgical laser system, configured
to generate a surgical laser beam, and
to guide the generated surgical laser beam into a cataract target region;
a laser controller, configured to scan the surgical laser beam in the cataract target region to create a photo-disrupted region;
a Spectral Domain Optical Coherence Tomographic (SD-OCT) imaging system, configured to generate an image of the photo-disrupted region for a system operator in a surgical time after the scanning of the surgical laser beam started with an image resolution in the range of 0.5-5 million image points per image and a frame-rate in the range of 20-200frames/sec; wherein
the laser controller is configured to stop the scanning of the surgical laser beam in response to receiving a stop-control signal from the system operator in response to the generated image.