Medical dressing containing antimicrobial agent and related methods therefor
View Patent ↗A medical dressing containing an antimicrobial agent is disclosed. The medical dressing comprises a layered fabric comprising an inner layer of substantially hydrophilic material, an outer layer of substantially hydrophobic material on both sides of the inner layer; and an antimicrobial agent. The antimicrobial agent may be releasably impregnated into the fabric, coated on said fabric or a combination thereof. The antimicrobial agent may be a biguanide, such as polyhexamethylene biguanide (PHMB). The fabric inner layer material may be substantially a cellulose fiber, preferably substantially rayon, and the fabric outer layer material may be substantially polyester, e.g., a combination of textile matrix grade polyester fiber and amorphous binder grade polyester fiber. The fabric is preferably treated with an aqueous solution of surfactant and PHMB to have about 1500-3500 ppm of extractable PHMB.
1. A medical dressing consisting essentially of:
an inner layer of hydrophilic material;
outer layers of hydrophobic material on both sides of the inner layer; and
an antimicrobial agent,
wherein the antimicrobial agent is releasably contained in the inner layer, and
wherein the antimicrobial agent contains a biguanide.
2. The medical dressing according to claim 1 wherein the antimicrobial agent is coated on the inner layer.
3. The medical dressing according to claim 1 wherein the biguanide is polyhexamethylene biguanide.
4. The medical dressing according to claim 1 wherein at least one of the outer layers is a combination of textile matrix grade polyester fiber and amorphous binder grade polyester fiber.
5. The medical dressing according to claim 1 , wherein the antimicrobial agent further includes a surfactant, the dressing having about 1500-3500 ppm of extractable biguanide.
6. The medical dressing according to claim 1 wherein the inner layer of hydrophilic material is rayon, and wherein the outer layers of hydrophobic material are a combination of textile matrix grade polyester fiber and amorphous binder grade polyester fiber.
7. A sponge comprising plies of a layered fabric consisting essentially of:
an inner layer of hydrophilic material;
outer layers of hydrophobic material on both sides of the inner layer; and
a biguanide antimicrobial agent releasably contained in the inner layer.
8. The sponge according to claim 7 wherein the biguanide antimicrobial agent is polyhexamethylene biguanide.
9. The sponge according to claim 7 wherein the sponge comprises 6 plies of the layered fabric.
10. The sponge according to claim 7 having a cross-shaped incision in the center of the layered fabric.
11. The medical dressing according to claim 1 wherein at least one of the outer layers has a hydrophilic finish.
12. The sponge according to claim 7 wherein at least one of the outer layers has a hydrophilic finish.
13. The sponge according to claim 7 wherein the inner layer of hydrophilic material is rayon, and wherein the outer layers of hydrophobic material are a combination of textile matrix grade polyester fiber and amorphous binder grade polyester fiber.