Method of differentiating between blood and control solutions containing a common analyte
View Patent ↗Glucose measured in blood samples is distinguished from glucose measured in the control solutions used to test the optical instruments which make such measurements. The control solutions contain a labeling substance recognized by the optical instrument to distinguish glucose measurements made of control solutions from those made of blood samples.
1. A method of measuring the glucose in blood by an optical instrument, the method comprising the acts of testing the performance of the instrument by adding a control solution containing a known amount of glucose to a test strip adapted to react with the glucose and produce an optical response from an indicator and measuring the response, the control solution contains a labeling substance recognized by the optical instrument and distinguished from the response of the indicator, wherein the labeling substance has a peak absorbance of light that is distinguished from the absorbance of the indicator.
2. The method of claim 1 , wherein the labeling substance is indocyanine green.
3. The method of claim 2 , wherein the labeling substance is distinguished from a tetrazolium salt indicator.
4. The method of claim 1 , wherein the labeling substance has a characteristic response to excitation by a light-emitting diode in the optical instrument that is distinguishable from the response of the indicator.
5. The method of claim 1 , further comprising compiling the glucose measurements, the glucose measurements excluding control solution measurements.
6. The method of claim 1 , wherein the labeling substance is a dye adapted to be dissolved in the control solution.