IP Library Granted Patent US 8,545,248
Granted Patent B2
US 8,545,248 · App. 13/340,484 · Granted Oct 1, 2013

System to control fluid flow based on a leak detected by a sensor

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Quick Facts
Patent No.
US 8,545,248
App. No.
13/340,484
Granted
Oct 1, 2013
Kind
B2
Abstract

A system including a communication interface to communicatively couple to a sensor cartridge, a fluidic subsystem to exchange a reagent solution with the sensor cartridge, and a computational circuitry communicatively coupled to the communication interface and the fluidic subsystem. The computation circuitry is to monitor a sensor signal of a sensor of the sensor cartridge, detect a leak based on the sensor signal, and control fluid flow of the fluidic subsystem in response to detecting.

Claims (33)

1. A system comprising:

a communication interface to communicatively couple to a sensor cartridge;

a fluidic subsystem to exchange a reagent solution with the sensor cartridge; and

a computational circuitry communicatively coupled to the communication interface and the fluidic subsystem;

wherein the computation circuitry is to monitor a sensor signal of a sensor of the sensor cartridge, detect a leak based on the sensor signal, and control fluid flow of the fluidic subsystem in response to detecting.

2. The system of claim 1 , wherein the sensor cartridge includes a sensor exposed to the reagent solution.

3. The system of claim 1 , wherein the sensor cartridge includes an array of sensors, the sensor being of the array of sensors.

4. The system of claim 3 , wherein the sensor is a reference sensor of the array of sensors.

5. The system of claim 1 , wherein the sensor is an ion sensitive sensor.

6. The system of claim 1 , wherein the sensor is a temperature sensor.

7. The system of claim 1 , wherein the computational circuitry is to detect the leak based on a loss of the sensor signal.

8. The system of claim 1 , wherein the computational circuitry is to detect the leak based on a change in characteristic of the sensor signal.

9. The system of claim 8 , wherein the change in characteristic is a change in noise.

10. The system of claim 9 , wherein the noise is line noise.

11. The system of claim 8 , wherein the change in characteristic is a change in value beyond a threshold.

12. The system of claim 1 , further comprising a setting to receive the sensor cartridge in alignment with the communication interface.

13. The system of claim 1 , wherein the fluidic subsystem includes a manifold having fluid ports to engage the sensor cartridge.

14. The system of claim 1 , further comprising a user interface to provide an override option to a user.

15. A method of controlling a system, the method comprising:

establishing communicative coupling between a communication interface and a sensor cartridge;

establishing fluid communication between a fluidic subsystem and a sensor cartridge;

monitoring a sensor signal of the sensor cartridge via the communication interface;

detecting a leak based on a characteristic of the sensor signal; and

controlling fluid flow of the fluidic subsystem in response to detecting the leak.

16. The method of claim 15 , wherein the characteristic is noise and wherein detecting a leak includes detecting an increase in noise.

17. The method of claim 16 , wherein the noise includes line noise.

18. The method of claim 16 , wherein the noise includes crosstalk from another sensor signal.

19. The method of claim 15 , wherein detecting includes detecting a loss of the sensor signal.

20. The method of claim 15 , wherein the characteristic is a value, and wherein detecting the leak includes detecting a value beyond a threshold.

21. A computer readable medium comprising non-transitory computer operable instructions operable by a computational circuitry to perform a method comprising:

monitoring a sensor signal of a sensor cartridge via a communication interface, the sensor cartridge communicatively coupled to the communication interface and in fluid communication with a fluid subsystem;

detecting a leak based on a characteristic of the sensor signal; and

controlling fluid flow of the fluidic subsystem in response to detecting the leak.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 25, 2012
From: DAVEY, MELVILLE; ROTH, GEORGE; MARRAN, DAVID; MILESKI, WILLIAM; NOBILE, JOHN
To: LIFE TECHNOLOGIES CORPORATION
Reel/Frame 027590/0475 →