IP Library Granted Patent US 8,638,998
Granted Patent B2
US 8,638,998 · App. 13/345,843 · Granted Jan 28, 2014

Fusion of multiple imaging planes for isotropic imaging in MRI and quantitative image analysis using isotropic or near-isotropic imaging

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Quick Facts
Patent No.
US 8,638,998
App. No.
13/345,843
Granted
Jan 28, 2014
Kind
B2
Abstract

In accordance with the present invention there is provided methods for generating an isotropic or near-isotropic three-dimensional images from two-dimensional images. In accordance with the present invention the method includes, obtaining a first image of a body part in a first plane, wherein the first image generates a first image data volume; obtaining a second image of the body part in a second plane, wherein the second image generates a second image data volume; and combining the first and second image data volumes to form a resultant image data volume, wherein the resultant image data volume is isotropic or near-isotropic.

Claims (33)

1. A method of making a joint replacement device, including:

obtaining data of a first image volume;

obtaining data of a second image volume; and

transforming the data of the first image volume and the data of the second image volume into a common coordinate system, wherein the data referenced in the common coordinate system are used to design or select a joint replacement device.

2. The method of claim 1 , including using anatomical landmarks for said transforming of the data of the first image volume and the data of the second image volume into said common coordinate system.

3. The method of claim 1 , wherein said transforming of the data of the first image volume and the data of the second image volume into said common coordinate system is achieved with use of user defined landmarks.

4. The method of claim 1 , wherein said transforming of the data of the first image volume and the data of the second image volume into a common coordinate system is achieved with use of a priori knowledge.

5. The method of claim 4 , wherein said a priori knowledge includes knowledge of the image position.

6. The method of claim 4 , wherein said a priori knowledge include knowledge of the image orientation.

7. The method of claim 1 , wherein the data of the first image volume is image data selected from the group consisting of x-ray, CT, spiral CT and MRI image data, and wherein the data of the second image volume is image data selected from the group consisting of x-ray, CT, spiral CT and MRI image data.

8. The method of claim 1 , where the data of the first image volume and the data of the second image volume are obtained from two different planes.

9. A method of designing or selecting a joint replacement device, including

obtaining data of a first image volume;

obtaining data of a second image volume;

transforming the data of the first image volume and the data of the second image volume into a common coordinate system, and

performing at least one or more segmentations of data, wherein data referenced in the common coordinate system and generated by the segmentation are used to design a joint replacement device.

10. The method of claim 9 , wherein the data of the first image volume is image data selected from the group consisting of x-ray, CT, spiral CT and MRI image data, and wherein the data of the second image volume is image data selected from the group consisting of x-ray, CT, spiral CT and MRI image data.

11. The method of claim 9 , where the data of the first image volume and the data of the second image volume are obtained from two different planes.

12. The method of claim 9 , including using anatomical landmarks for said transforming of the data of the first image volume and the data of the second image volume into said common coordinate system.

13. The method of claim 9 , wherein said transforming of the data of the first image volume and the data of the second image volume into said common coordinate system is achieved with use of user defined landmarks.

14. The method of claim 9 , wherein said transforming of the data of the first image volume and the data of the second image volume into a common coordinate system is achieved with use of a priori knowledge.

15. The method of claim 14 , wherein said a priori knowledge includes knowledge of the image position and/or image orientation.

16. A method of designing or selecting a joint replacement device, including

obtaining data of a first image volume;

obtaining data of a second image volume;

transforming the data of the first image volume and the data of the second image volume into a common coordinate system, and

performing at least one or more segmentations of data, wherein data referenced in the common coordinate system and generated by the segmentation are used to select a joint replacement device.

17. The method of claim 16 , wherein the data of the first image volume is image data selected from the group consisting of x-ray, CT, spiral CT and MRI image data, and wherein the data of the second image volume is image data selected from the group consisting of x-ray, CT, spiral CT and MRI image data.

18. The method of claim 16 , where the data of the first image volume and the data of the second image volume are obtained from two different planes.

19. The method of claim 16 , including using anatomical landmarks for said transforming of the data of the first image volume and the data of the second image volume into said common coordinate system.

20. The method of claim 16 , wherein said transforming of the data of the first image volume and the data of the second image volume into said common coordinate system is achieved with use of user defined landmarks.

21. The method of claim 16 , wherein said transforming of the data of the first image volume and the data of the second image volume into a common coordinate system is achieved with use of a priori knowledge.

22. The method of claim 21 , wherein said a priori knowledge includes knowledge of the image position and/or image orientation.

Assignments (7)
RELEASE OF SECURITY INTEREST Recorded Sep 6, 2023
From: MIDCAP FINANCIAL TRUST, AS AGENT FOR LENDERS
To: CONFORMIS, INC.; IMATX, INC.
Reel/Frame 064818/0713 →
RELEASE OF SECURITY INTEREST Recorded Nov 23, 2021
From: CONFORMIS, INC.; IMATX, INC.; CONFORMIS CARES LLC
To: INNOVATUS LIFE SCIENCES LENDING FUND I, LP
Reel/Frame 058234/0292 →
SECURITY INTEREST Recorded Nov 22, 2021
From: CONFORMIS, INC.; IMATX, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 058219/0346 →
RELEASE OF SECURITY INTEREST Recorded Jun 26, 2019
From: OXFORD FINANCE LLC, AS COLLATERAL AGENT
To: CONFORMIS, INC.
Reel/Frame 049599/0084 →
SECURITY INTEREST Recorded Jun 25, 2019
From: CONFORMIS, INC.; IMATX, INC.; CONFORMIS CARES LLC
To: INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT
Reel/Frame 049588/0288 →
SECURITY INTEREST Recorded Jul 31, 2018
From: CONFORMIS, INC.
To: OXFORD FINANCE LLC, AS COLLATERAL AGENT
Reel/Frame 046676/0152 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 24, 2012
From: LANG, PHILIPP
To: CONFORMIS, INC.
Reel/Frame 028095/0553 →