IP Library › Granted Patent US 8,563,590
Granted Patent B2
US 8,563,590 · App. 13/348,945 · Granted Oct 22, 2013

Compounds, compositions and methods for the treatment of islet amyloid polypeptide (IAPP) accumulation in diabetes

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Quick Facts
Patent No.
US 8,563,590
App. No.
13/348,945
Granted
Oct 22, 2013
Kind
B2
Abstract

Dihydroxyaryl compounds and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of IAPP or amylin fibril diseases, and the manufacture of medicaments for such treatment.

Claims (2)

1. A method of treating the formation, deposition, accumulation, or persistence of IAPP amyloid or amylin/IAPP fibrils, comprising treating the fibrils with an effective amount of 2,4 bis (3,4 dihydroxyphenyl) imidazole.

2. A method of treating type II diabetes in a mammal suffering therefrom, comprising administration to the mammal of a therapeutically effective amount of 2,4 bis (3,4dihydroxyphenyl) imidazole.

Assignments (2)
CHANGE OF NAME Recorded Jun 9, 2016
From: PROTEOTECH, INC.
To: PROTAMED, INC.
Reel/Frame 038944/0598 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 19, 2012
From: LAKE, THOMAS; SNOW, ALAN D.
To: PROTEOTECH, INC.
Reel/Frame 027887/0160 →