Prodrugs of 2,4-pyrimidinediamine compounds and their uses
View Patent ↗The present disclosure provides prodrugs of biologically active 2,4-pyrimidinediamine compounds, compositions comprising the prodrugs, intermediates and methods for synthesizing the prodrugs and methods of using the prodrugs in a variety of applications.
1. A compound of the formula
or a pharmaceutically acceptable salt thereof, wherein the compound or pharmaceutically acceptable salt thereof is in the form of a hydrate.
2. The compound of claim 1 , wherein the compound is a free acid.
3. The compound of claim 1 , wherein the compound is a pharmaceutically acceptable salt.
4. The compound of claim 3 , wherein the pharmaceutically acceptable salt is an alkali metal salt.
5. The compound of claim 4 , wherein the pharmaceutically acceptable salt is a sodium salt.
6. The compound of claim 5 , wherein the pharmaceutically acceptable salt is a disodium salt.
7. The compound of claim 3 , wherein the pharmaceutically acceptable salt is an alkaline earth metal salt.
8. The compound of claim 7 , wherein the pharmaceutically acceptable salt is a calcium salt.