IP Library › Granted Patent US 8,354,550
Granted Patent B2
US 8,354,550 · App. 13/349,651 · Granted Jan 15, 2013

Skin treatments containing carboxylic acid-substituted idebenone derivatives and methods of preparation and use thereof

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Quick Facts
Patent No.
US 8,354,550
App. No.
13/349,651
Granted
Jan 15, 2013
Kind
B2
Abstract

The present invention relates to novel carboxylic acid-substituted idebenone derivatives, skin treatment compositions containing these carboxylic acid-substituted idebenone derivatives, methods of treating skin changes by topical application of these carboxylic acid-substituted idebenone derivatives, and their methods of synthesis. The carboxylic acid-substituted idebenone derivatives of the present invention are unexpectedly effective in treating skin, particularly with respect to skin tolerance. When included in a topical composition, the carboxylic acid-substituted idebenone derivatives of the present invention have an antioxidant effect that is useful in treating a skin change.

Claims (5)

1. A compound of general Formula I:

wherein R 1 is a C 2-22 straight or branched sugar acid, and wherein two or more hydroxy groups on the sugar acid are each independently substituted with a C 1-22 carboxylic acid.

2. The compound of claim 1 , wherein one or more carboxylic acid is a fatty acid.

3. The compound of claim 2 , wherein one or more fatty acid is a conjugate fatty acid.

4. The compound of claim 1 , wherein the compound of general Formula I is idebenone dipalmitoyl glycerate.

Assignments (21)
SECURITY INTEREST Recorded Oct 2, 2024
From: BRANDCO ALMAY 2020 LLC; BRANDCO CND 2020 LLC; BRANDCO ELIZABETH ARDEN 2020 LLC; BRANDCO MITCHUM 2020 LLC; REVLON CONSUMER PRODUCTS LLC
To: MUFG BANK LTD. AS AGENT
Reel/Frame 069102/0838 →
RELEASE OF SECURITY INTEREST Recorded Oct 1, 2024
From: MIDCAP FUNDING IV TRUST, AS COLLATERAL AGENT
To: BRANDCO ALMAY 2020 LLC; BRANDCO CND 2020 LLC; BRANDCO ELIZABETH ARDEN 2020 LLC; BRANDCO MITCHUM 2020 LLC; REVLON CONSUMER PRODUCTS LLC; CREATIVE NAIL DESIGN, INC.; SINFULCOLORS, INC.
Reel/Frame 069084/0092 →
ABL PATENT SECURITY AGREEMENT Recorded May 4, 2023
From: BRANDCO ALMAY 2020 LLC; BRANDCO CND 2020 LLC; BRANDCO ELIZABETH ARDEN 2020 LLC; BRANDCO MITCHUM 2020 LLC; REVLON CONSUMER PRODUCTS LLC; CREATIVE NAIL DESIGN, INC.; SINFULCOLORS, INC.
To: MIDCAP FUNDING IV TRUST
Reel/Frame 063548/0557 →
TERM LOAN PATENT SECURITY AGREEMENT Recorded May 4, 2023
From: BRANDCO ALMAY 2020 LLC; BRANDCO CND 2020 LLC; BRANDCO ELIZABETH ARDEN 2020 LLC; BRANDCO MITCHUM 2020 LLC; REVLON CONSUMER PRODUCTS LLC; CREATIVE NAIL DESIGN, INC.; SINFULCOLORS, INC.
To: JEFFERIES FINANCE LLC
Reel/Frame 063548/0575 →
STATEMENT REGARDING RELEASE OF LIENS ON COPYRIGHTS, TRADEMARKS AND PATENTS Recorded May 3, 2023
From: REVLON GROUP HOLDINGS LLC
To: ALMAY, INC.; ART & SCIENCE, LTD.; BARI COSMETICS, LTD.; BEAUTYGE BRANDS USA, INC.; BEAUTYGE I; BEAUTYGE II, LLC; BEAUTYGE USA, INC.; BRANDCO ALMAY 2020 LLC; BRANDCO CHARLIE 2020 LLC; BRANDCO CND 2020 LLC; BRANDCO CURVE 2020 LLC; BRANDCO ELIZABETH ARDEN 2020 LLC; BRANDCO GIORGIO BEVERLY HILLS 2020 LLC; BRANDCO HALSTON 2020 LLC; BRANDCO JEAN NATE 2020 LLC; BRANDCO MITCHUM 2020 LLC; BRANDCO MULTICULTURAL GROUP 2020 LLC; BRANDCO PS 2020 LLC; BRANDCO WHITE SHOULDERS 2020 LLC; CHARLES REVSON INC.; CREATIVE NAIL DESIGN, INC.; CUTEX, INC.; DF ENTERPRISES, INC.; ELIZABETH ARDEN (CANADA) LIMITED; ELIZABETH ARDEN (FINANCING), INC.; ELIZABETH ARDEN (UK) LTD.; ELIZABETH ARDEN INVESTMENTS, LLC; ELIZABETH ARDEN NM, LLC; ELIZABETH ARDEN TRAVEL RETAIL, INC.; ELIZABETH ARDEN USC, LLC; ELIZABETH ARDEN, INC.; FD MANAGEMENT, INC.; NORTH AMERICA REVSALE INC.; OPP PRODUCTS, INC.; PPI TWO CORPORATION; RDEN MANAGEMENT, INC.; REALISTIC ROUX PROFESSIONAL PRODUCTS INC.; REVLON (PUERTO RICO) INC.; REVLON CANADA INC.; REVLON CONSUMER PRODUCTS CORPORATION; REVLON DEVELOPMENT CORP.; REVLON GOVERNMENT SALES, INC.; REVLON INTERNATIONAL CORPORATION; REVLON PROFESSIONAL HOLDING COMPANY LLC; REVLON, INC.; RIROS CORPORATION; RIROS GROUP INC.; RML, LLC; ROUX LABORATORIES, INC.; ROUX PROPERTIES JACKSONVILLE, LLC; SINFULCOLORS INC.
Reel/Frame 063530/0396 →
SECURITY INTEREST Recorded Jul 1, 2022
From: BRANDCO ELIZABETH ARDEN 2020 LLC
To: JEFFERIES FINANCE LLC, AS COLLATERAL AGENT
Reel/Frame 060426/0543 →
RELEASE OF SECURITY INTEREST Recorded May 18, 2020
From: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT
To: CREATIVE NAIL DESIGN, INC.; ELIZABETH ARDEN, INC.; FD MANAGEMENT, INC.; REVLON CONSUMER PRODUCTS CORPORATION; ROUX LABORATORIES, INC.; SINFULCOLORS INC.
Reel/Frame 052694/0508 →
FIRST LIEN PATENT SECURITY AGREEMENT Recorded May 11, 2020
From: BRANDCO ELIZABETH ARDEN 2020 LLC
To: JEFFERIES FINANCE LLC
Reel/Frame 052621/0118 →
THIRD LIEN PATENT SECURITY AGREEMENT Recorded May 11, 2020
From: BRANDCO ELIZABETH ARDEN 2020 LLC
To: JEFFERIES FINANCE LLC
Reel/Frame 052620/0520 →
SECOND LIEN PATENT SECURITY AGREEMENT Recorded May 11, 2020
From: BRANDCO ELIZABETH ARDEN 2020 LLC
To: JEFFERIES FINANCE LLC
Reel/Frame 052620/0478 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 9, 2020
From: BEAUTYGE I
To: BRANDCO ELIZABETH ARDEN 2020 LLC
Reel/Frame 052618/0730 →
BACK-UP PATENT SECURITY AGREEMENT Recorded May 9, 2020
From: BEAUTYGE I
To: BRANDCO ELIZABETH ARDEN 2020 LLC
Reel/Frame 052619/0470 →
BACK-UP PATENT SECURITY AGREEMENT Recorded May 8, 2020
From: ELIZABETH ARDEN, INC.
To: BEAUTYGE I
Reel/Frame 052617/0084 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 8, 2020
From: ELIZABETH ARDEN, INC.
To: BEAUTYGE I
Reel/Frame 052614/0645 →
RELEASE OF SECURITY INTEREST IN CERTAIN PATENTS AT R/F 040220/0478 Recorded May 7, 2020
From: CITIBANK N.A., AS COLLATERAL AGENT
To: ELIZABETH ARDEN, INC.
Reel/Frame 052599/0530 →
RELEASE OF SECURITY INTEREST IN CERTAIN PATENTS AT R/F 040219/0253 Recorded May 7, 2020
From: CITIBANK N.A., AS COLLATERAL AGENT
To: ELIZABETH ARDEN, INC.
Reel/Frame 052599/0491 →
SECURITY INTEREST Recorded Aug 6, 2019
From: CREATIVE NAIL DESIGN, INC.; ELIZABETH ARDEN, INC.; FD MANAGEMENT, INC.; REVLON CONSUMER PRODUCTS CORPORATION; ROUX LABORATORIES, INC.; SINFULCOLORS INC.
To: WILMINGTON TRUST, NATIONAL ASSOCIATION
Reel/Frame 049969/0038 →
PATENT SECURITY AGREEMENT Recorded Oct 4, 2016
From: ELIZABETH ARDEN, INC.
To: CITIBANK, N.A., AS COLLATERAL AGENT
Reel/Frame 040219/0253 →
PATENT SECURITY AGREEMENT (TERM) Recorded Oct 4, 2016
From: ELIZABETH ARDEN, INC.
To: CITIBANK, N.A., AS COLLATERAL AGENT
Reel/Frame 040220/0478 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 13, 2012
From: DIEDRICH, FALKO; NEUDECKER, BIRGIT; WIELAND, EBERHARD; LEWIS, II, JOSEPH A.; DINARDO, JOSEPH C.; THOMPSON, ANDREW S.; KERSCHEN, JAMES ALAN; WADE, PETER C.
To: PCR TECHNOLOGY HOLDINGS, LC
Reel/Frame 027853/0482 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 13, 2012
From: PCR TECHNOLOGY HOLDINGS, LC
To: ELIZABETH ARDEN, INC.
Reel/Frame 027853/0867 →