IP Library Patent Application 13351924
Patent Application
App. No. 13/351,924

TRANSDERMAL RICINOLEIC ACID COMPOSITIONS

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Patent No.
US None
App. No.
13/351,924
Abstract

Transdermal compositions containing castor oil are described. The compositions comprise ricinoleic acid and a transdermal vehicle with optional additional agents. One optional additional agent is an adrenergic drug which may cause the ricinoleic acid to penetrate the skin more deeply and have a longer lasting effect. The compositions can be used for treating a variety of ailments traditionally treated with castor oil or castor oil packs, without the mess and inconvenience of using castor oil packs.

Claims (21)

1 - 22 . (canceled)

23 . A method for treating an ailment comprising topically administering to a subject having the ailment a transdermal composition comprising:

a transdermal vehicle; and

ricinoleic acid in an amount effective to treat the ailment.

24 . The method of treating an ailment of claim 23 , wherein the transdermal vehicle is a lecithin organogel.

25 . The method of treating an ailment of claim 23 , wherein the transdermal vehicle is selected from the group consisting of: lotions; liposomes; vesicles; phospholipids; transferosomes; solid lipid nanoparticles; fatty acids; fatty acid esters; oleic acid; terpenes; limonene; surfactants; polysorbate; Sodium Dodecyl Sulfate; DMSO; ethanol; lauracapram and its derivatives; and 2-n-nonyl-1,3-dioxolane and its derivatives; and mixtures thereof.

26 . The method of treating an ailment of claim 23 , wherein the ailment is selected from the group consisting of: lymphatic congestion; swollen lymph nodes; headache; migraine headache; sore throat; chronic fluid retention; arthritis; upper respiratory infections; Crohn's disease; colitis; gallbladder disease; boils; liver cirrhosis, liver hepatitis; liver enlargement; liver congestion; menstrual-related congestion; appendicitis; hyperactivity; constipation, bowel impaction; bowel adhesions; bladder infections; vaginal infections; muscle strains; ligament sprains; immune system depression; nerve inflammation; sciatica; shingles; Parkinson's disease; multiple sclerosis; cerebral palsy; skin keratosis; ringworm; fungal and bacterial infections; cuts; wounds; abdominal stretch marks; bursitis; sebaceous cysts; warts; senile lentigo; and itching.

27 . The method of treating an ailment of claim 23 , further comprising an adrenergic drug.

28 . The method of treating an ailment of claim 27 , wherein the adrenergic drug is selected from the group consisting of: phenylephrine, epinephrine, norepinephrine, phenylpropanolamine, ephedrine, pseudoephedrine, and oxymetcoline.

29 . The method of treating an ailment of claim 27 , wherein the adrenergic drug is present in an amount of about 0.001% to about 0.1% of the weight of the final composition.

30 . The method of treating an ailment of claim 23 , further comprising guaifenesin.

31 . The method of treating an ailment of claim 23 , further comprising a therapeutic agent.

32 . The method of treating an ailment of claim 31 , wherein the therapeutic agent is selected from the group consisting of: copper, magnesium, manganese, selenium, sodium, potassium, zinc, nickel, cobalt and iron, and pharmaceutically acceptable salts thereof.

33 . The method of treating an ailment of claim 31 , wherein the therapeutic agent is a homeopathic agent.

34 . The method of treating an ailment of claim 33 , wherein the homeopathic agent is selected from the group consisting of kali muriaticum, sulphur, agentum nitricum, hippozenum, and mixtures thereof.

35 . The method of treating an ailment of claim 31 , wherein the therapeutic agent in an amount of about 10 −10 % to about 30% of the weight of the final composition.

36 . The method of treating an ailment of claim 23 , further comprising guaifenesin.

37 . The method of treating an ailment of claim 26 , wherein the guaifenesin is present in an amount of about 0.01% to about 30% of the weight of the final composition.

38 . The method of treating an ailment of claim 23 , wherein the transdermal vehicle is present in an amount of about 10% to about 70% of the weight of the final composition.

39 . The method of treating an ailment of claim 23 , wherein the ricinoleic acid is in the form of castor oil.

40 . The method of treating an ailment of claim 39 , wherein the castor oil is present in an amount of about 30% to about 75% of the weight of the final composition.

Assignments (2)
SECURITY INTEREST RELEASE REEL/FRAME 029340/0249 Recorded Jul 17, 2015
From: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
To: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; DIRECT RADIOGRAPHY CORP.; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
Reel/Frame 036128/0001 →
FIRST SUPPLEMENT TO PATENT SECURITY AGREEMENT Recorded Nov 20, 2012
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; DIRECT RADIOGRAPHY CORP.; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
To: GOLDMAN SACHS BANK USA
Reel/Frame 029340/0249 →