IP Library Granted Patent US 8,334,353
Granted Patent B2
US 8,334,353 · App. 13/365,250 · Granted Dec 18, 2012

Polyfarnesenes by metal-catalyzed insertion polymerizations

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Quick Facts
Patent No.
US 8,334,353
App. No.
13/365,250
Granted
Dec 18, 2012
Kind
B2
Abstract

Provided herein are polyfarnesenes such as farnesene homopolymers derived from a farnesene and farnesene interpolymers derived from a farnesene and at least a vinyl monomer; and the processes of making and using the polyfarnesenes. The farnesene homopolymer can be prepared by polymerizing the farnesene in the presence of a catalyst such as a Ziegler-Natta catalyst, a Kaminsky catalyst, a metallocene catalyst, an organolithium reagent or a combination thereof. In some embodiments, the farnesene is prepared from a sugar by using a microorganism.

Claims (22)

1. A method of making a polyfarnesene comprising polymerizing a farnesene in the presence of a catalyst, wherein the farnesene is α-farnesene or β-farnesene or a combination thereof, and wherein an amount of a cis-1,4-microstructure in the polyfarnesene is at most about 80 wt. %, based on a total weight of the polyfarnesene.

2. The method of claim 1 , wherein the catalyst is a Ziegler-Natta catalyst, a Kaminsky catalyst, a metallocene catalyst, an organolithium reagent or a combination thereof.

3. The method of claim 1 , wherein the catalyst is a Ziegler-Natta catalyst.

4. The method of claim 3 , wherein the Ziegler-Natta catalyst comprises (1) a transition metal compound comprising an element from groups IV to VIII of the periodic table; and (2) an organometallic compound comprising a metal from groups I to III of the periodic table.

5. The method of claim 4 , wherein the transition metal compound further comprises one or more anions and ligands.

6. The method of claim 5 , wherein the one or more anions and ligands are selected from halides, oxyhalides, alkoxy, acetylacetonyl, cyclopentadienyl and phenyl.

7. The method of claim 6 , wherein the element from groups IV to VIII is titanium, vanadium, chromium, molybdenum, zirconium, iron or cobalt.

8. The method of claim 4 , wherein the organometallic compound is a hydride, alkyl or aryl of the metal from groups I to III, wherein the metal is selected from aluminum, lithium, zinc, tin, cadmium, beryllium and magnesium.

9. The method of claim 4 , wherein the organometallic compound is an alumoxane, an alkylaluminum compound, diethylzinc, di(i-butyl)zinc, di(n-hexyl)zinc or ethylzinc (t-butoxide).

10. The method of claim 9 , wherein the alkylaluminum compound is trimethylaluminum, triethylaluminum, diethyl aluminum chloride, trimethylaluminum, triisobutylaluminum or trioctylaluminum.

11. The method of claim 1 , wherein the catalyst is a Kaminsky catalyst.

12. The method of claim 11 , wherein the Kaminsky catalyst has formula Cp 2 MX 2 or formula (XVI):

where each M is a transition metal; each X is a halogen, alkyl or a combination thereof; each R is H or alkyl; each Cp is a ferrocenyl group; and Z is a divalent bridging group selected from C(CH 3 ) 2 , Si(CH 3 ) 2 or CH 2 CH 2 .

13. The method of claim 12 , wherein the transition metal is Zr, Ti or Hf.

14. The method of claim 1 , wherein the catalyst is a metallocene catalyst.

15. The method of claim 1 , wherein the catalyst is an organolithium reagent.

16. The method of claim 15 , wherein the catalyst further comprises 1,2-bis(dimethylamino)ethane.

17. The method of claim 15 , wherein the organolithium reagent is n-butyl lithium or sec-butyl lithium.

18. The method of claim 1 further comprising a step of making the farnesene from a simple sugar by a microorganism.

19. A polyfarnesene prepared by the method of claim 1 .

20. The method of claim 1 , wherein the farnesene is copolymerized with at least one vinyl monomer and wherein the at least one vinyl monomer is ethylene, an α-olefin, a substituted or unsubstituted vinyl halide, vinyl ether, acrylonitrile, acrylic ester, methacrylic ester, acrylamide or methacrylamide or a combination thereof.

21. The method of claim 1 , wherein the farnesene is copolymerized with at least one vinyl monomer wherein the at least one vinyl monomer is ethylene or styrene.

Assignments (16)
SECURITY INTEREST Recorded May 24, 2024
From: AMYRIS, INC.
To: EUAGORE, LLC
Reel/Frame 067528/0467 →
RELEASE OF SECURITY INTEREST Recorded Feb 14, 2023
From: SCHOTTENFELD OPPORTUNITIES FUND II, L.P.
To: AMYRIS, INC.
Reel/Frame 062760/0818 →
RELEASE OF SECURITY INTEREST Recorded Feb 14, 2023
From: NAXYRIS S.A.
To: AMYRIS, INC.
Reel/Frame 062760/0753 →
SECURITY INTEREST Recorded Oct 18, 2022
From: AMYRIS, INC.
To: FORIS VENTURES, LLC
Reel/Frame 061703/0499 →
GRANT OF PATENT SECURITY INTEREST Recorded Nov 20, 2019
From: AMYRIS, INC.
To: SCHOTTENFELD OPPORTUNITIES FUND II, L.P.
Reel/Frame 051072/0310 →
RELEASE OF SECURITY INTEREST Recorded Aug 28, 2019
From: STEGODON CORPORATION
To: AMYRIS, INC.
Reel/Frame 050206/0606 →
SECURITY INTEREST Recorded Aug 16, 2019
From: AMYRIS, INC.
To: NAXYRIS S.A.
Reel/Frame 050081/0106 →
SECURITY INTEREST Recorded Jun 16, 2016
From: HERCULES CAPITAL INC.
To: STEGODON CORPORATION
Reel/Frame 039048/0251 →
SECURITY INTEREST Recorded Jun 3, 2016
From: AMYRIS, INC.
To: HERCULES TECHNOLOGY GROWTH CAPITAL, INC.
Reel/Frame 038878/0381 →
RELEASE OF SECURITY INTEREST Recorded Mar 31, 2014
From: MAXWELL (MAURITIUS) PTE LTD
To: AMYRIS, INC.
Reel/Frame 032578/0357 →
RELEASE OF SECURITY INTEREST Recorded Mar 28, 2014
From: TOTAL ENERGIES NOUVELLES ACTIVITES USA, SAS (F/K/A TOTAL GAS & POWER USA, SAS)
To: AMYRIS, INC.
Reel/Frame 032554/0001 →
RELEASE OF SECURITY INTEREST Recorded Mar 27, 2014
From: TOTAL ENERGIES NOUVELLES ACTIVITIES USA, SAS (F/K/A TOTAL GAS & POWER USA, SAS)
To: AMYRIS, INC.
Reel/Frame 032551/0828 →
SECURITY AGREEMENT Recorded Nov 8, 2013
From: AMYRIS, INC.
To: TOTAL ENERGIES NOUVELLES ACTIVITES USA
Reel/Frame 031607/0314 →
SECURITY AGREEMENT Recorded Oct 23, 2013
From: AMYRIS, INC.
To: MAXWELL (MAURITIUS) PTE LTD
Reel/Frame 031478/0933 →
SECURITY AGREEMENT Recorded May 8, 2013
From: AMYRIS, INC.
To: TOTAL GAS & POWER USA, SAS
Reel/Frame 030378/0447 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 21, 2012
From: MCPHEE, DEREK JAMES
To: AMYRIS, INC.
Reel/Frame 028237/0843 →