IP Library Granted Patent US 9,120,067
Granted Patent B2
US 9,120,067 · App. 13/395,592 · Granted Sep 1, 2015

Micro mixer and microfluidic chip

Inventors: Kenichi Miyata (Amagasaki, JP); Takahiro Mohri (Izumi, JP); Kusunoki Higashino (Osaka, JP); Yasuhiro Sando (Amagasaka, JP); Masashi Nishikado (Osaka, JP); Gou Yanagihara (Sakai, JP)
Assignee: KONICA MINOLTA, INC.
B01F15/00876B01F5/0065B01F11/0074B01J19/0093B01L3/5027B01J2219/00783B01J2219/00889B01L2200/027B01L2200/0636B01L2200/0684B01L2300/0816B01L2300/0858B01L2300/0867B01L2400/049
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Quick Facts
Patent No.
US 9,120,067
App. No.
13/395,592
Granted
Sep 1, 2015
Kind
B2
Abstract

There are provided a micro mixer capable of efficiently mixing at least two types of liquids in a simple structure and a microfluidic chip provided with the micro mixer. In order to achieve the object, the micro mixer includes a minute passage through which first and second liquids are caused to flow respectively, and a mixing vessel in which a liquid injecting port caused to communicate with the minute passage is provided in a bottom part, and the liquid injecting port is provided in a shifted position from a center of the bottom part in the bottom part. Moreover, the liquid injecting port may be provided in a shifted position from a center line of the mixing vessel.

Claims (44)

1. A micro mixer comprising:

a minute passage through which first and second liquids are caused to flow; and

a mixing vessel in which a liquid injecting port caused to communicate with said minute passage is provided in a bottom part in depth direction of said mixing vessel;

wherein said minute passage includes a first passage portion extending in a horizontal direction and a second passage portion extending vertically upward on one end of said first passage portion, and

wherein said liquid injecting port is provided to communicate with said second passage portion, and is provided in a shifted position from a center of said bottom part in said bottom part.

2. The micro mixer according to claim 1 , wherein at least one convex portion is provided in the bottom part of said mixing vessel.

3. The micro mixer according to claim 1 , wherein a first variation of an angle formed by an internal wall surface of said mixing vessel and a horizontal surface in a passage advanced by a predetermined distance in a first direction from said liquid injecting port over said internal wall surface of said mixing vessel is different from a second variation of an angle formed by said internal wall surface of said mixing vessel and said horizontal surface in a path advanced by said predetermined distance in a second direction which is opposite to said first direction from said liquid injecting port over said internal wall surface of said mixing vessel.

4. The micro mixer according to claim 3 , wherein said first variation is relatively greater than said second variation, and

an inclined portion tapered toward said liquid injecting port is provided in said second direction based on said liquid injecting port in the bottom part of said mixing vessel.

5. The micro mixer according to claim 1 , wherein an internal wall surface of said mixing vessel has water repellency.

6. The micro mixer according to claim 1 , wherein said liquid injecting port discharges a liquid stored in said mixing vessel toward said minute passage.

7. The micro mixer according to claim 1 , further comprising:

a first supplying path configured to supply said first liquid to said minute passage; and

a second supplying path configured to supply said second liquid to said minute passage.

8. A microfluidic chip comprising:

the micro mixer according to claim 1 ; and

a reactor, which is provided in the vicinity of an internal wall surface of said minute passage through which a mixed liquid generated by mixing said first and second liquids in said mixing vessel is to be discharged from said mixing vessel, to which a reactant for carrying out a reaction to a substance contained in said mixed liquid is fixed.

9. A micro mixer comprising:

a minute passage through which first and second liquids are caused to flow; and

a mixing vessel in which a liquid injecting port caused to communicate with said minute passage is provided in a bottom part in depth direction of said mixing vessel;

wherein said minute passage includes a first passage portion extending in a horizontal direction and a second passage portion extending vertically upward on one end of said first passage portion, and

wherein said liquid injecting port is provided to communicate with said second passage portion, and is provided in a shifted position from a center line of said mixing vessel.

10. The micro mixer according to claim 9 , wherein at least one convex portion is provided in the bottom part of said mixing vessel.

11. The micro mixer according to claim 9 , wherein a first variation of an angle formed by an internal wall surface of said mixing vessel and a horizontal surface in a passage advanced by a predetermined distance in a first direction from said liquid injecting port over said internal wall surface of said mixing vessel is different from a second variation of an angle formed by said internal wall surface of said mixing vessel and said horizontal surface in a path advanced by said predetermined distance in a second direction which is opposite to said first direction from said liquid injecting port over said internal wall surface of said mixing vessel.

12. The micro mixer according to claim 11 , wherein said first variation is relatively greater than said second variation, and

an inclined portion tapered toward said liquid injecting port is provided in said second direction based on said liquid injecting port in the bottom part of said mixing vessel.

13. The micro mixer according to claim 9 , wherein an internal wall surface of said mixing vessel has water repellency.

14. The micro mixer according to claim 9 , wherein said liquid injecting port discharges a liquid stored in said mixing vessel toward said minute passage.

15. The micro mixer according to claim 9 , further comprising:

a first supplying path configured to supply said first liquid to said minute passage; and

a second supplying path configured to supply said second liquid to said minute passage.

16. A microfluidic chip comprising:

the micro mixer according to claim 9 ; and

a reactor, which is provided in the vicinity of an internal wall surface of said minute passage through which a mixed liquid generated by mixing said first and second liquids in said mixing vessel is to be discharged from said mixing vessel, to which a reactant for carrying out a reaction to a substance contained in said mixed liquid is fixed.

17. A micro mixer comprising:

a minute passage through which first and second liquids are caused to flow; and

a mixing vessel in which a liquid injecting port caused to communicate with said minute passage is provided in a bottom part in depth direction of said mixing vessel;

wherein said minute passage includes a first passage portion extending in a horizontal direction and a second passage portion extending vertically upward on one end of said first passage portion,

wherein said liquid injecting port is provided to communicate with said second passage portion; and

wherein in a section in a horizontal direction of an internal space region surrounded by an internal wall surface of said mixing vessel, a first distance from a position through which a virtual line that is virtually extended upward from a center of said liquid injecting port passes to said internal wall surface in relation to a one direction is different from a second distance from a position through which said virtual line passes to said internal wall surface in relation to an opposite direction to said one direction.

18. The micro mixer according to claim 17 , wherein at least one convex portion is provided in the bottom part of said mixing vessel.

19. The micro mixer according to claim 17 , wherein a first variation of an angle formed by said internal wall surface of said mixing vessel and a horizontal surface in a passage advanced by a predetermined distance in a first direction from said liquid injecting port over said internal wall surface of said mixing vessel is different from a second variation of an angle formed by said internal wall surface of said mixing vessel and said horizontal surface in a path advanced by said predetermined distance in a second direction which is opposite to said first direction from said liquid injecting port over said internal wall surface of said mixing vessel.

20. The micro mixer according to claim 19 , wherein said first variation is relatively greater than said second variation, and

an inclined portion tapered toward said liquid injecting port is provided in said second direction based on said liquid injecting port in the bottom part of said mixing vessel.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 21, 2022
From: KONICA MINOLTA, INC.
To: OTSUKA PHARMACEUTICAL CO., LTD.
Reel/Frame 059747/0589 →
MERGER Recorded Jul 22, 2015
From: KONICA MINOLTA HOLDINGS, INC.
To: KONICA MINOLTA, INC.
Reel/Frame 036154/0015 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 12, 2012
From: MIYATA, KENICHI; MOHRI, TAKAHIRO; HIGASHINO, KUSUNOKI; SANDO, YASUHIRO; NISHIKADO, MASASHI; YANAGIHARA, GOU
To: KONICA MINOLTA HOLDINGS, INC.
Reel/Frame 027847/0229 →
Priority Claims (1)
JP 2009-219924 · Sep 25, 2009 · national
Continuity (1)
Related Publication 20120201724A1 · Aug 9, 2012