Ocular system with anchoring implant and therapeutic agent
Ocular implants, delivery devices and methods for treating ocular disorders are disclosed. One method involves inserting an implant on one side of an eye. The implant has an anchor on a distal end portion and an outlet opening that is disposed proximal of the anchor. The implant is advanced across the eye to the other side of the eye. The anchor is inserted into eye tissue on the other side of the eye. A therapeutic agent is eluted using the implant.
1. A system for treating an ocular disorder, comprising:
an implant comprising an anchor on a distalmost end portion of the implant, the distalmost end portion being closed;
a therapeutic agent; and
a delivery device comprising an elongate body and configured to insert the implant on one side of an eye, advance the implant across the eye to an other side of the eye, and insert the anchor into eye tissue on the other side of the eye so that the anchor penetrates only partially into a sclera of the eye.
2. The system of claim 1 , wherein the therapeutic agent is part of the implant.
3. The system of claim 2 , wherein the implant has a body and the therapeutic agent is part of the body of the implant.
4. The system of claim 1 , wherein the therapeutic agent is appended to the implant.
5. The system of claim 1 , wherein the therapeutic agent is coated on a surface of the implant.
6. The system of claim 1 , wherein at least a portion of the implant is configured to elute the therapeutic agent into the eye.
7. The system of claim 1 , wherein the implant is configured to deliver the therapeutic agent through the outlet opening.
8. The system of claim 1 , wherein a portion of the delivery device is configured to transport the therapeutic agent into the eye.
9. The system of claim 1 , wherein the implant comprises a controller to control fluid flow through the implant.
10. The system of claim 1 , wherein the controller comprises a valve.
11. The system of claim 1 , wherein the anchor comprises a structure selected from the group consisting of a conical shape, a screw, at least one protrusion, and a circumferential indentation.
12. The system of claim 1 , wherein the anchor comprises a sharp end.
13. The system of claim 12 , wherein the sharp end of the anchor is at a distal-most end of the distal end portion.
14. The system of claim 1 , wherein the implant comprises at least one inlet opening in fluid communication with an outlet opening disposed proximal of the anchor.
15. The system of claim 1 , wherein the delivery device is configured to advance the implant across an anterior chamber of the eye.
16. The system of claim 1 , wherein the delivery device is configured to access an anterior chamber of the eye and introduce the implant into the anterior chamber through the incision.