Human immunodeficiency virus type 1 clade M mosaic gag polypeptides
View Patent ↗The present invention relates to mosaic HIV-1 group M Gag sequences and to a composition comprising same.
1. An isolated mosaic clade M human immunodeficiency virus type 1 (HIV-1) Gag polypeptide comprising an amino acid sequence selected from the group consisting of Gag M 3.1 (SEQ ID NO:72), Gag M 3.2 (SEQ ID NO:73) and Gag M 3.3 (SEQ ID NO:74).
2. The polypeptide according to claim 1 wherein said polypeptide comprises the amino acid sequence of Gag M 3.1 (SEQ ID NO:72).
3. A composition comprising at least one polypeptide according to claim 1 and a carrier.
4. A method of inducing an immune response in a mammal comprising administering to said mammal an amount of at least one polypeptide or protein according to claim 1 sufficient to effect said induction.
5. The polypeptide according to claim 1 wherein said polypeptide comprises the amino acid sequence of Gag M 3.2 (SEQ ID NO:73).
6. The polypeptide according to claim 1 wherein said polypeptide comprises the amino acid sequence of Gag M 3.3 (SEQ ID NO:74).