Magnesium compositions and uses thereof for neurological disorders
A composition for administration to a subject, such as oral administration to a subject, for example, has been provided. Such a composition may comprise at least one magnesium-counter ion compound. A magnesium-counter ion composition described herein may be useful for any of a variety of applications provided herein, such as maintaining, enhancing, and/or improving health, nutrition, and/or another condition of a subject, and/or cognitive, learning, and/or memory function. A magnesium-counter ion composition provided herein may be useful for administration to a subject presenting magnesium deficiency, mild cognitive impairment, Alzheimer's disease, attention deficit hyperactivity disorder, ALS, Parkinson's disease, diabetes, migraine, anxiety disorder, mood disorder, and/or hypertension. A kit, method, and other associated technology are also provided.
1. A dosage form formulated for oral administration to a subject comprising magnesium threonate, wherein the dosage form comprises at least 10 mg magnesium threonate, and wherein the dosage form is a solid, semi-solid, semi-liquid, or a gel.
2. The dosage form of claim 1 , comprising at least 500 mg magnesium threonate.
3. The dosage form of claim 1 , comprising about 10 mg to about 800 mg magnesium threonate.
4. The dosage form of claim 1 , wherein the dosage form comprises about 30 mg to about 1.5 g of elemental magnesium.
5. The dosage form of claim 1 , wherein the dosage form comprises about 50 mg to about 800 mg elemental magnesium.
6. The dosage form of claim 1 , wherein the dosage form is a solid.
7. The dosage form of claim 1 , wherein the dosage form is a gel, semi-liquid or semi-solid.
8. The dosage form of claim 1 , comprising elemental magnesium at a concentration of at least about 5 mg/L.
9. The dosage form of claim 1 , comprising elemental magnesium at a concentration of from about 5 mg/L to about 12 g/L.
10. The dosage form of claim 1 , further comprising a nutritionally active agent.
11. The dosage form of claim 10 , wherein the nutritionally active agent is selected from the group consisting of: a calcium-containing material, an herbal, a spice, vitamin A, vitamin D, a vitamin E, a vitamin K, a vitamin B, folic acid, niacin, biotin, a mineral, and mixtures thereof.
12. The dosage form of claim 1 that is a tablet.
13. The dosage form of claim 1 that is a capsule.
14. A method of providing magnesium supplementation to a subject, comprising: orally administering to the subject the dosage form of claim 1 .
15. The method of claim 14 wherein the subject suffers from Attention Deficit Hyperactivity Disorder (ADHD), Parkinson's disease (PD), schizophrenia, fatigue, hypertension, or anxiety.
16. The method of claim 14 , comprising providing about 1.5 mg/kg of body weight/day to about 18 mg/kg of body weight/day of elemental magnesium.
17. The method of claim 14 , wherein the dosage form is administered for at least about 15 days.
18. The method of claim 14 , wherein the dosage form is administered for at least about 4 months.
19. The dosage form of claim 1 , wherein the dosage form is a dietary supplement.