IP Library Granted Patent US 9,226,791
Granted Patent B2
US 9,226,791 · App. 13/418,136 · Granted Jan 5, 2016

Systems for temperature-controlled ablation using radiometric feedback

Inventors: John F. McCarthy (Newbury, NH); Timothy J. Lenihan (Hradec Kralove, CZ); Eric R. Kanowsky (Santa Barbara, CA); Robert C. Allison (Rancho Palos Verdes, CA)
Assignees: Advanced Cardiac Therapeutics, Inc.; Meridian Medical Systems, LLC
A61B18/082A61B18/12A61B18/02A61B18/1206A61B18/1492A61B18/1815A61B2017/0007A61B2017/00486A61B2018/00357A61B2018/00577A61B2018/00642A61B2018/00678A61B2018/00708A61B2018/00714A61B2018/00797A61B2018/00821A61B2018/00839A61B2218/002A61N7/022
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Quick Facts
Patent No.
US 9,226,791
App. No.
13/418,136
Granted
Jan 5, 2016
Kind
B2
Abstract

The present invention provides systems and methods for temperature-controlled ablation using radiometric feedback. An interface module may include (a) a processor; (b) a first input/output (I/O) port to receive digital radiometer and digital thermocouple signals from an integrated catheter tip (ICT); (c) a second I/O port to receive ablative energy from a generator; (d) a temperature display; (e) a patient relay; (f) a computer-readable medium storing instructions for causing the processor to: (i) calculate a temperature adjacent to the ICT based on the digital radiometer and thermocouple signals and operation parameters; (ii) cause the temperature display to display the calculated temperature; and (iii) close the patient relay to pass ablative energy received on the second I/O port to the first I/O port; and (g) a temperature control subsystem to regulate the ablative power based on the calculated temperature.

Claims (20)

1. An ablation system for regulating delivery of ablative energy to targeted tissue of a subject, comprising:

an ablation energy source configured to generate ablative energy to be delivered to targeted tissue of a subject via an ablation member of a catheter;

a processor;

wherein the processor is configured to calculate a temperature of the targeted tissue of the subject at a depth relative to a surface of the targeted tissue based on, at least in part, a signal generated by a radiometer at a tip of the catheter and a signal generated by a temperature-measurement device at the tip of the catheter; and

wherein the system is configured to automatically regulate operation of the ablation member to deliver the ablative energy based upon at least the calculated temperature.

2. The system of claim 1 ,

wherein the catheter comprises a fluid passage, and wherein the catheter tip comprises at least one irrigation fluid port, the at least one irrigation fluid port being in fluid communication with the fluid passage of the catheter;

wherein the fluid passage of the catheter is configured to be placed in fluid communication with an irrigation pump, the irrigation pump being configured to selectively deliver irrigation fluid through the fluid passage of the catheter and the at least one irrigation fluid port of the catheter tip.

3. The system of claim 1 , wherein the ablation member comprises one of a radiofrequency electrode, a microwave ablation member, a cryoablation member and an ultrasound ablation member.

4. The system of claim 1 , wherein the system is configured to automatically regulate the operation of the ablation member to maintain the calculated temperature of the targeted tissue within a target temperature setpoint or range.

5. The system of claim 1 , further comprising a temperature display for displaying the calculated temperature of tissue.

6. The system of claim 1 , wherein the system is operatively coupled to an electrophysiology monitoring system.

7. An ablation system for regulating delivery of ablative energy to targeted tissue of a subject, comprising:

an ablation energy source configured to generate ablative energy to be delivered to targeted tissue of a subject via an ablation member of a catheter;

wherein the system is configured to calculate a temperature of the targeted tissue of the subject at a depth relative to a surface of the targeted tissue based on, at least in part, a signal generated by a radiometer and a signal generated by a temperature-measurement device; and

wherein the system is configured to automatically regulate operation of the ablation member to deliver the ablative energy based upon at least the calculated temperature.

8. The system of claim 7 , wherein the system is configured to automatically regulate the operation of the ablation member to maintain the calculated temperature of the targeted tissue within a target temperature setpoint or range.

9. The system of claim 7 , wherein the ablation member comprises one of a radiofrequency electrode, a microwave ablation member, a cryoablation member and an ultrasound ablation member.

10. The system of claim 7 , further comprising an irrigation system comprising a pump in fluid communication with a fluid passage of the catheter, wherein the irrigation system is configured to selectively deliver irrigation fluid through the fluid passage of the catheter and at least one irrigation fluid port of the catheter in fluid communication with the fluid passage of the catheter during use.

11. The system of claim 7 , further comprising a temperature display for displaying the calculated temperature of tissue.

Assignments (5)
RELEASE OF SECURITY INTEREST Recorded Oct 11, 2018
From: ABBOTT LABORATORIES
To: EPIX THERAPEUTICS, INC., FORMERLY ADVANCED CARDIAC THERAPEUTICS, INC.
Reel/Frame 047218/0808 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 24, 2017
From: MERIDIAN MEDICAL SYSTEMS LLC
To: CORAL SAND BEACH, LLC
Reel/Frame 041808/0910 →
SECURITY INTEREST Recorded Jan 10, 2017
From: ADVANCED CARDIAC THERAPEUTICS, INC.
To: ABBOTT LABORATORIES
Reel/Frame 040936/0054 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 19, 2014
From: ALLISON, ROBERT C.
To: MERIDIAN MEDICAL SYSTEMS, LLC
Reel/Frame 034561/0548 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 11, 2012
From: MCCARTHY, JOHN; LENIHAN, TIMOTHY J.; KANOWSKY, ERIC R.
To: ADVANCED CARDIAC THERAPEUTICS, INC.
Reel/Frame 028030/0437 →
Continuity (1)
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