Stabilized hypohalous acid solutions
View Patent ↗The present invention provides a stabilized hypohalous acid solution (or formulation thereof), which may be conveniently packaged for sale, or stored for later use on demand. The invention further provides methods of making the stabilized hypohalous acid solution, as well as methods of use for disinfecting mammalian tissue, including wounds and burns, disinfecting or cleansing surfaces, or treating and/or preserving food products and cut flowers, among other uses.
1. A stabilized solution or hydrogel formulation in a container packaged for sale, comprising hypochlorous acid prepared by electrolysis of a NaCl solution and a stabilizing amount of dissolved inorganic carbon (DIC) added in the form of a bicarbonate or carbonate of an alkali or alkaline earth metal,
wherein the solution or hydrogel formulation has: an available free chlorine (AFC) content of from 100 to 500 parts per million, a pH of from 5 to 7, a salinity of from about 0.02 to about 1.0%, from 300 mg/L to 1500 mg/L of said bicarbonate or carbonate, wherein the ratio of DIC to AFC is not more than 5:1;
and wherein the container is nonpermeable by CO 2 or O 2 .
2. The stabilized solution or formulation of claim 1 , wherein said AFC content and said pH are stable for at least 6 months.
3. The stabilized solution or formulation of claim 1 , wherein the DIC is added as sodium bicarbonate.
4. The stabilized solution or formulation of claim 3 , wherein the sodium bicarbonate is contained within the NaCl electrolyte.
5. The stabilized solution or formulation of claim 3 , wherein the sodium bicarbonate is added after electrolysis.
6. The stabilized solution or formulation of claim 1 , wherein the solution or formulation: has an AFC content of from 100 to 500 parts per million, a pH in the range of from 5 to 6.4, a salinity of from about 0.02 to about 1.0%, and from 300 to 1000 mg/L of sodium bicarbonate.
7. A method for disinfecting or cleansing a mammalian tissue, comprising, applying the solution or formulation of claim 1 to the mammalian tissue.
8. The method of claim 7 , wherein the mammalian tissue is infected.
9. The method of claim 7 , wherein the tissue comprises a wound or burn.
10. The method of claim 7 , wherein the solution or formulation is applied to the affected area of a mammal having one or more dermatoses.
11. A method of treating a food product comprising applying the solution of claim 1 to the food product.
12. The stabilized solution or formulation of claim 1 , wherein the container is a bottle, a bag, a tube, or a can.
13. The stabilized solution or formulation of claim 12 , wherein the container is a bottle.