Methods for inhibiting sensory nerves by topically administering strontium-containing compositions to keratinized skin
View Patent ↗Topical formulations containing aqueous-soluble divalent strontium cation in a suitable topical keratinized skin formulation vehicle, and methods of using these formulations to inhibit skin irritation in keratinized skin, are disclosed.
1. A method for inhibiting sensory nerves that respond to irritants comprising the steps of:
preparing a composition comprising:
an aqueous-soluble strontium cation;
a skin penetration enhancer; and
a delivery vehicle; and
topically administering the composition to keratinized skin.
2. The method according to claim 1 , wherein the composition further comprises a counteranion.
3. The method according to claim 2 , wherein the counterion further comprises an inorganic anion.
4. The method according to claim 3 , wherein the inorganic anion further comprises a halogen selected from the group consisting of: F, Cl, Br, and I.
5. The method according to claim 3 , wherein the inorganic anion further comprises a nitrate.
6. The method according to claim 4 , wherein the halogen is Cl.
7. The method according to claim 1 , wherein the delivery vehicle is water.
8. The method according to claim 1 , wherein the composition further comprises an organic solvent.
9. The method according to claim 8 , wherein the organic solvent is a glycol.
10. The method according to claim 6 , wherein the delivery vehicle is water.
11. A method for inhibiting sensory nerves that respond to irritants comprising the steps of:
preparing a composition comprising:
an aqueous-soluble strontium cation; and
a delivery vehicle; and
topically administering the composition to keratinized skin.