IL-B30 antibodies
View Patent ↗Purified genes encoding interleukin-B30 from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using said reagents and diagnostic kits are also provided.
1. A recombinant antibody, or antigen binding fragment thereof, that specifically binds to a polypeptide comprising residues 1-175 of SEQ ID NO: 4.
2. The recombinant antibody, or antigen binding fragment thereof, of claim 1 , wherein said antibody specifically binds to a polypeptide consisting of residues 1-175 of SEQ ID NO: 4.
3. The recombinant antibody, or antigen binding fragment thereof, of claim 1 , wherein the antibody or fragment binds said polypeptide with an affinity of at least 3 nM.
4. The recombinant antibody, or antigen binding fragment thereof, of claim 1 , wherein said antibody is a monoclonal antibody.
5. The recombinant antibody, or antigen binding fragment thereof, of claim 1 , wherein said antibody is a chimeric antibody.
6. A sterile composition comprising the recombinant antibody, or antigen binding fragment thereof, of claim 1 .
7. A recombinant full length antibody that specifically binds to a polypeptide comprising residues 1-175 of SEQ ID NO: 4.
8. An antigen binding fragment of a recombinant antibody that specifically binds to a polypeptide comprising residues 1-175 of SEQ ID NO: 4, wherein the antigen binding fragment is:
a) a Fab fragment;
b) a Fab 2 fragment; or
c) a single chain antibody.