Embolic coil detachment mechanism with polymer tether
View Patent ↗Provided herein are a system and method for detaching a therapeutic device, e.g. an embolic coil, from a delivery tube at a target site in a patient's body. The system includes a bead disposed against a distal end of the therapeutic device that retains the therapeutic device to the delivery tube in a first compressed configuration through a series of connectors. The series of connectors include a stretch resistant member through which the bead is attached to an anchor inside the therapeutic device. The anchor, in turn, is disposed against a thermally responsive element comprised of a polymeric material configured to melt or otherwise change configuration to release the anchor, and with it, to also release the bead and therapeutic device. Energy may be supplied to the thermally responsive element through electrical conductors and a resistive heating element disposed within the delivery tube.
1. A therapeutic actuator, comprising a polymeric element having a tether portion that secures a therapeutic element to a heating and delivery system, further comprising:
a flexible tube defining a lumen therein wherein the therapeutic element is configured to fit adjacent the lumen of the flexible tube and to be released at a distal end of the flexible tube;
the heating and delivery system comprising an electrical conductor disposed within the lumen of the flexible tube and a resistive heating element also disposed within the lumen of the flexible tube distal to the electrical conductor and electrically connected to the electrical conductor;
the polymeric element further comprising an aggregate portion, wherein the tether portion is adjacent to the resistive heating element and the aggregate portion is positioned inside the therapeutic element and distal to the tether portion;
an anchor disposed in the aggregate portion of the polymeric element; and
a bead disposed on a distal end of the therapeutic element that maintains the therapeutic element in a first configuration through a stretch resistant member that secures the bead to the anchor.
2. The therapeutic actuator of claim 1 , wherein the therapeutic actuator is configured such that melting the polymeric element through energy supplied by the electrical conductor that heats the resistive heating element results in the tether portion breaking to deploy the therapeutic element at the distal end of the flexible tube.
3. The therapeutic actuator of claim 1 , wherein the anchor has a horseshoe shape.
4. The therapeutic actuator of claim 1 , wherein a distal face of the bead has a hemispherical shape.
5. The therapeutic actuator of claim 1 , wherein a distal face of the bead has a rounded outer surface that facilitates atraumatic introduction of the therapeutic element.
6. The therapeutic actuator of claim 1 , wherein the therapeutic element is an embolic coil configured for treatment of aneurysm.