HIGHLY PURIFIED ETHYL EPA AND OTHER EPA DERIVATIVES
A pharmaceutical preparation comprising EPA in an appropriately assimilable form where of all the fatty acids present in the preparation at least 90%, and preferably at least 95%, is in the form of EPA and where less than 5%, and preferably less than 3%, is in the form of DHA is provided.
1 . A pharmaceutical composition comprising eicosapentaenoic acid, wherein the composition contains no docosahexaenoic acid and the composition is present in a capsule.
2 . The composition of claim 1 wherein the composition contains less than 5% of any fatty acid other than eicosapentaenoic acid.
3 . The composition of claim 1 wherein the composition contains less than 3% of any fatty acid other than eicosapentaenoic acid.
4 . The composition of claim 2 wherein the eicosapentaenoic acid comprises ethyl-eicosapentaenoic acid, lithium-eicosapentaenoic acid, mono-, di- or triglyceride eicosapentaenoic acid, or an ester, salt or free acid of eicosapentaenoic acid.
5 . The composition of claim 4 wherein the eicosapentaenoic acid comprises ethyl-eicosapentaenoic acid or an ester thereof.
6 . The composition of claim 5 wherein the capsule is a gelatin capsule.
7 . The composition of claim 5 where the composition comprises at least 90% wt/wt ethyl-eicosapentaenoic acid or an ester thereof.
8 . The composition of claim 5 where the composition comprises at least 95% wt/wt ethyl-eicosapentaenoic acid or an ester thereof.
9 . The composition of any one of claims 1 - 8 wherein the eicosapentaenoic acid is present in the composition in an amount of 250 mg to 1000 mg.
10 . A pharmaceutical composition comprising 250 mg to 1000 mg of eicosapentaenoic acid, wherein the composition contains no docosahexaenoic acid, less than 5% of any fatty acid other than eicosapentaenoic acid, and the composition is present in a capsule.
11 . A pharmaceutical composition comprising 250 mg to 1000 mg of ethyl-eicosapentaenoic acid or an ester thereof, wherein the composition contains no docosahexaenoic acid, less than 5% of any fatty acid other than ethyl-eicosapentaenoic acid or an ester thereof, and the composition is present in a capsule.