Fluorinated block co-polymers
View Patent ↗A block co-polymer includes a water soluble carrier block; an amino acid-based or acrylic acid-based block; and the amino acid-based or acrylic acid-based block includes a fluorinated alkyl group or a fluorinated alkylene glycol group.
1. A block co-polymer of formula:
wherein:
R 14 is H, alkyl, alkenyl, or a water-soluble group;
Q comprises a glutamic acid side chain, a aspartic acid side chain, a tyrosine side chain, a serine side chain, a threonine side chain, a lvsine side chain, a ornithine side chain, a histidine side chain, or an N-(3-hydroxypropyl)aspartamide side chain;
L is a bond; an alkylene; —O—; —C(O)—; —C(O)N(R 1 )(CH 2 ) n —; —N(R 2 )CO—; —C(O)O—; —C(O)O(CH 2 ) n —; —N(R 3 )C(O)O—; —N(R 4 )C(O)O(CH 2 ) n —; —OC(O)N(R 5 )(CH 2 ) n —; or
N(R 6 )C(O)N(R 7 )(CH 2 ) n —;
R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , and R 7 are each independently H or alkyl;
n is 0 or greater
Y is O, NH, or NC(O)alkyl;
X is NR 18 ;
R 18 is H or alkyl;
m and p are repeat block units in the polymer;
q is from 1 to 20;
and r is 0, 1, 2, or 3.
2. The block co-polymer of claim 1 , wherein n is 0, 1, 2, 3, 4, or 5.
3. The block co-polymer of claim 1 wherein R 14 is H or an alkenyl.
4. A composition comprising oxygenated micelles comprising:
block co-polymer of claim 1 ;
molecular oxygen; and
an aqueous vehicle.
5. The composition of claim 4 comprising 0.5 vol % to about 50 vol % of the molecular oxygen.
6. The composition of claim 4 , wherein the block copolymer comprises from about 0.5 wt % to about 50 wt % in the aqueous vehicle.