MACROMOLECULAR COMPOUND FOR DETECTING TARGET MATERIAL AND METHOD OF DETECTING TARGET MATERIAL BY USING THE SAME

1 . A macromolecular compound for detecting a target material, the macromolecular compound comprising a water-soluble copolymer comprising a first repeating unit to which a dye is bonded and a second repeating unit to which a probe is bonded.

2 . The macromolecular compound of claim 1 , wherein the first repeating unit and the second repeating unit are each independently acrylamide, poly-L-lysine, N-vinylpyrrolidone, N-acryloxysuccinimide, or pyrollo.

3 . The macromolecular compound of claim 1 , wherein the water-soluble copolymer comprises the first repeating unit to which the dye is bonded and the second repeating unit to which the probe at a molar ratio of between about 2:8 and about 8:2.

4 . The macromolecular compound of claim 1 , wherein the water-soluble copolymer of the macromolecular compound further comprises a third repeating unit.

5 . The macromolecular compound of claim 4 , wherein the third repeating unit is selected from the group consisting of acrylamide, poly-L-lysine, N-vinylpyrrolidone, N-acryloxysuccinimide, and pyrollo.

6 . The macromolecular compound of claim 4 , wherein the third repeating unit and the first and second repeating units to which the dye and probe are respectively bonded are irregularly arranged at a molar ratio of between 2:8 and 8:2.

7 . The macromolecular compound of claim 1 , wherein the water-soluble copolymer has a molecular weight of about 1,000 to about 1,000,000.

8 . The macromolecular compound of claim 1 , wherein the dye comprises at least one of a photochromic dye, an electrochromic dye, a thermochromic dye, or an indicator dye.

9 . The macromolecular compound of claim 1 , wherein the target material comprises a polynucleotide, protein, lipid, or carbohydrate.

10 . The macromolecular compound of claim 1 , wherein the macromolecular compound comprises two or more probes that specifically bond to different sites of the target material.

11 . The macromolecular compound of claim 1 , wherein the probe comprises a polynucleotide or antibody.

12 . A method of detecting a target material, the method comprising:

contacting a biological sample, which comprises a target material, with a macromolecular compound comprising a water-soluble copolymer comprising a first repeating unit to which a dye is bonded and a second repeating unit to which a probe for the target material is bonded; and

identifying a location of the target material in the biological sample in view of color of the macromolecular compound that is specifically bound to the target material.

13 . The method of claim 12 , wherein the biological sample is a cell or tissue.

14 . The method of claim 12 , wherein the method further comprises, after contacting the biological sample with the macromolecular compound, changing color of the macromolecular compound.

15 . The method of claim 14 , wherein changing of the color of the macromolecular compound comprises changing the pH of a solution comprising the macromolecular compound, electrically stimulating the macromolecular compound, changing the temperature of a solution including the macromolecular compound, or optically stimulating the macromolecular compound.