IP Library Granted Patent US 9,486,361
Granted Patent B2
US 9,486,361 · App. 13/445,816 · Granted Nov 8, 2016

Intraocular implants and methods and kits therefor

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Quick Facts
Patent No.
US 9,486,361
App. No.
13/445,816
Granted
Nov 8, 2016
Kind
B2
Abstract

Devices, methods and kits are described for reducing intraocular pressure. The devices include a support that is implantable within Schlemm's canal and maintains the patency of the canal without substantially interfering with transmural fluid flow across the canal. The devices utilize the natural drainage process of the eye and can be implanted with minimal trauma to the eye. Kits include a support and an introducer for implanting the support within Schlemm's canal. Methods include implanting a support within Schlemm's canal, wherein the support is capable of maintaining the patency of the canal without substantial interference with transmural fluid flow across the canal.

Claims (12)

1. A method for reducing intraocular pressure, comprising:

introducing a tubular cannula having a lumen at least partially within Schlemm's canal;

delivering a high viscosity fluid into Schlemm's canal; and

inserting a support into Schlemm's canal by passing the support through the tubular cannula, wherein the support comprises an arcuate member, wherein at least a portion of the arcuate member has a radius of curvature smaller than a radius of curvature of Schlemm's canal, and wherein the support comprises at least one fenestration.

2. The method of claim 1 , wherein the delivered fluid dilates the canal.

3. The method of claim 1 , wherein the high viscosity fluid is sodium hyaluronate.

4. The method of claim 1 , wherein the support is a rigid support.

5. The method of claim 1 , wherein the support contacts the interior wall of the canal at least at three points.

6. The method of claim 1 , wherein the support does not substantially interfere with longitudinal flow along the canal.

7. The method of claim 1 , wherein the support does not substantially interfere with transmural flow across the inner wall of the canal.

8. The method of claim 1 , wherein the support does not substantially interfere with transmural flow across the outer wall of the canal.

9. The method of claim 1 , wherein at least a portion of the support extends out of Schlemm's canal and into the trabecular meshwork.

Assignments (8)
SECURITY INTEREST Recorded Jan 23, 2024
From: SIGHT SCIENCES, INC.
To: HERCULES CAPITAL, INC., AS AGENT
Reel/Frame 066364/0162 →
RELEASE OF SECURITY INTEREST Recorded Jul 24, 2023
From: MIDCAP FUNDING IV TRUST
To: SIGHT SCIENCES, INC.
Reel/Frame 064354/0155 →
REAFFIRMED AND AMENDED SECURITY INTEREST (TERM) Recorded Nov 25, 2020
From: SIGHT SCIENCES, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 054524/0020 →
REAFFIRMED AND AMENDED SECURITY INTEREST (REVOLVING) Recorded Nov 25, 2020
From: SIGHT SCIENCES, INC.
To: MIDCAP FUNDING IV TRUST, AS AGENT
Reel/Frame 054524/0008 →
SECURITY AGREEMENT (TERM LOAN) Recorded Jan 28, 2019
From: SIGHT SCIENCES, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 048149/0209 →
SECURITY AGREEMENT (REVOLVING LOAN) Recorded Jan 28, 2019
From: SIGHT SCIENCES, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 048149/0230 →
SECURITY AGREEMENT (REVOLVING LOAN) Recorded Jan 28, 2019
From: SIGHT SCIENCES, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 049670/0542 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 13, 2012
From: BADAWI, DAVID Y.; BADAWI, PAUL
To: SIGHT SCIENCES, INC.
Reel/Frame 028046/0729 →