IP Library Granted Patent US 8,565,374
Granted Patent B2
US 8,565,374 · App. 13/462,342 · Granted Oct 22, 2013

Integrated multi-mode mammography/tomosynthesis x-ray system and method

View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 8,565,374
App. No.
13/462,342
Granted
Oct 22, 2013
Kind
B2
Abstract

A system for multi-mode breast x-ray imaging which comprises a compression arm assembly for compressing and immobilizing a breast for x-ray imaging, an x-ray tube assembly, and an x-ray image receptor is provided. The system is configured for a plurality of imaging protocols and modes.

Claims (36)

1. A system for multi-mode breast x-ray imaging, comprising:

a compression arm assembly for compressing and immobilizing a patient's breast for x-ray imaging;

an x-ray assembly; and

an x-ray image receptor;

wherein said compression arm assembly, said x-ray tube assembly and said x-ray image receptor are configured for movement to accommodate a plurality of imaging protocols and modes, and are angled relative to each other for different ones of said imaging protocols and modes; and

wherein said system is configured to deliver substantially lower x-ray dose to the patient's breast in taking a projection x-ray image of the breast when operating in a first one or said imaging modes than when operating in a second one of said imaging modes.

2. The system of claim 1 in which the system is configured to take plural tomosynthesis projection images of the breast during a single immobilization of the breast when operating in the first mode and a mammogram image of the breast when operating in the second mode, and wherein the total x-ray dose to the breast for the tomosynthesis projection images taken in the single breast immobilization is approximately the same as the x-ray dose for the mammogram taken in the second mode of operation.

3. The system of claim 1 in which the system is configured to take plural tomosynthesis projection images of the breast during a single immobilization of the breast when operating in the first mode and a mammogram image of the breast when operating in the second mode, and wherein the total x-ray dose to the breast for the tomosynthesis projection images taken in the single immobilization is no more than approximately three times the x-ray dose for the mammogram taken in the second mode of operation.

4. An x-ray breast imaging system comprising:

an x-ray source, an x-ray imaging receptor, and a breast immobilizer between the source and receptor;

said source being configured to selectively emit an imaging x-ray beam that passes through the breast immobilizer and impinges on the receptor, and the receptor being configured to generate a projection x-ray image in response to the imaging beam;

said system being configured to operate in a first imaging mode in which the system takes a first projection x-ray image at a selected first position of the x-ray source relative to the breast immobilizer and in a second imaging mode in which the system takes a plural projection images each taken at a different position of the source relative to the breast immobilizer;

wherein the x-ray dose for one of the plural projection images is substantially lower than for said first projection image.

5. The system of claim 4 in which the total x-ray dose for the plural images is approximately one to three times the x-ray dose for said first image.

6. The system of claim 4 in which the total x-ray dose for the plural images is approximately the same as the x-ray dose for the first image.

7. The system of claim 4 in which the first image is a mammogram and the plural images are tomosynthesis projection images.

8. The system of claim in which the plural images comprise at least 11 tomosynthesis projection images.

9. The system of claim 4 in which the plural images comprise between 11 and 21 tomosynthesis projection images.

10. The system of claim 4 in which the system is configured to take said plural images during a continuous motion of the source relative to the breast immobilizer.

11. The system of claim 10 in which the system is configured to take said plural images while the imaging beam continuously impinges on the breast immobilizer.

12. The system of claim 10 in which the system is configured to take said plural images while the imaging beam intermittently impinges on the breast immobilizer.

13. The system of claim 12 in which the system is configured to take said plural images in the course of an intermittent motion of the source relative to the breast immobilizer.

14. The system of claim 4 comprising a gantry supporting the source, receptor and immobilizer, and a data acquisition work station coupled with the gantry and configured to control the gantry and to receive and process said images.

15. The system of claim 4 in which the immobilizer comprises a breast platform having a front for facing a patient and a width, and a compression paddle that is smaller in width than the platform and is mounted for selective motion along the platform width.

16. The system of claim 4 including a paddle support configured to move the paddle along the platform width.

17. The system of claim 4 in which the support is motorized to move the paddle along the platform width.

18. The system of claim 4 in which the support comprises manually operated devices for moving the paddle along the platform width.

19. The system of claim 4 in which said system is configured to set a collimation of the imaging beam matching a size of the paddle.

20. The system of claim 19 in which the system is configured to automatically set the collimation of the imaging beam to match the size of the paddle.

21. A multi-mode breast x-ray imaging system comprising:

an x-ray source, an x-ray imaging receptor, and a breast immobilizer between the source and receptor;

said system being configured to change, in response to operator selection, from one to the other of (a) a standard mammography mode in which the source, immobilizer and receptor are mounted for rotation as a unit, and (b) a tomosynthesis mode in which the source and receptor are mounted for rotation relative to the immobilizer; and

said system being further configured to take a standard mammogram in said mammogram mode but to take plural tomosynthesis projection images in said tomosynthesis mode during a single immobilization of a patient's breast.

22. The system of claim 21 including an anti-scatter grid between the immobilizer and the receptor.

23. The system of claim 21 in which the system is configured to operate in the absence of an anti-scatter grid between the breast and the imaging receptor in at least one of said mammogram mode and tomosynthesis mode.

24. The system of claim 21 in which the x-ray dose for taking plural projection images in a single immobilization in the tomosynthesis mode is approximately one to three times the x-ray dose for taking a mammogram in said mammogram mode.

Assignments (7)
RELEASE OF SECURITY INTEREST Recorded Apr 28, 2026
From: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
To: HOLOGIC, INC., ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO DIRECT RADIOGRAPHY CORP.; CYTYC CORPORATION, ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO BIOLUCENT, LLC; CYTYC SURGICAL PRODUCTS, LLC, AS SUCCESSOR-BY-CONVERSION TO CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; GEN-PROBE INCORPORATED, ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE PRODESSE, INC.; SUROS SURGICAL SYSTEMS, INC.
Reel/Frame 075566/0039 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT PATENT NO. 8081301 PREVIOUSLY RECORDED AT REEL: 028810 FRAME: 0745. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY AGREEMENT. Recorded Nov 9, 2017
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
To: GOLDMAN SACHS BANK USA
Reel/Frame 044432/0565 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT PATENT NO. 8081301 PREVIOUSLY RECORDED AT REEL: 035820 FRAME: 0239. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY INTEREST RELEASE. Recorded Nov 9, 2017
From: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
To: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
Reel/Frame 044727/0529 →
SECURITY AGREEMENT Recorded Aug 7, 2015
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; DIRECT RADIOGRAPHY CORP.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 036307/0199 →
SECURITY INTEREST RELEASE REEL/FRAME 028810/0745 Recorded Jun 4, 2015
From: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
To: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
Reel/Frame 035820/0239 →
SECURITY AGREEMENT Recorded Aug 1, 2012
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
To: GOLDMAN SACHS BANK USA
Reel/Frame 028810/0745 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 19, 2012
From: DEFREITAS, KENNETH; FARBIZIO, TOM; REN, BAORI; RUTH, CHRIS; SHAW, IAN; SMITH, ANDREW; STEIN, JAY
To: HOLOGIC, INC.
Reel/Frame 028597/0618 →