Sample plate systems and methods
A sample plate comprising a sample well is disclosed. The sample well can comprise one or more bead retaining chambers. Also provided herein is a method of using the sample plate and kits comprising the sample plate.
1. A method of detecting an analyte comprising:
(a) adding a sample to a sample plate comprising a sample well, wherein said sample well comprises a base portion, wherein said base portion comprises a plurality of recesses, each recess having a circular cross-section, wherein beads are located in at least some of said plurality of recesses and wherein each of said recesses comprises:
i) a tapered section or
ii) a diameter less than a diameter of a respective one of said beads located in said recess; and
(b) detecting binding of an analyte in said sample with at least one probe.
2. The method of claim 1 , wherein said sample plate comprises a plurality of probes and a plurality of analytes are detected.
3. The method of claim 1 , wherein a plurality of samples is added to said sample plate.
4. The method of claim 1 , wherein said plurality of recesses are arranged circumferentially around a central portion of the sample well.