IP Library Granted Patent US 8,788,283
Granted Patent B2
US 8,788,283 · App. 13/464,554 · Granted Jul 22, 2014

Modifiable attribute identification

Inventors: Andrew Alexander Kenedy (Sugar Land, TX); Charles Anthony Eldering (Furlong, PA)
Assignee: Expanse Bioinformatics, Inc.
G06Q40/00G06Q40/08G09B19/00
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Quick Facts
Patent No.
US 8,788,283
App. No.
13/464,554
Granted
Jul 22, 2014
Kind
B2
Abstract

A method, software, database and system for determining modifiable lifestyle attributes which when altered, can increase the longevity of an individual is presented. Based on an individual's pangenetic (genetic and epigenetic) attributes and by comparison with databases of attributes and longevity data, specific modifiable attributes which increase longevity, based on the individual's specific pangenetic makeup, can be identified.

Claims (26)

1. A non-transitory computer readable medium having computer-executable instructions for generating a pangenetic based determination of one or more modifiable lifestyle attributes for an individual, which when modified provide a recommended personalized treatment regimen for a disease, comprising:

a) a previously stored database of attribute profiles and disease data for a population of individuals, wherein each attribute profile comprises pangenetic and modifiable lifestyle attributes that are correlated with at least a portion of the disease data, the pangenetic attribute(s) further comprising genetic or epigenetic attributes; and

b) a set of instructions that, when executed by a processor, cause that processor to perform the steps of:

i) receiving a query associated with the individual and the disease;

ii) accessing an attribute profile associated with the individual, wherein the attribute profile contains pangenetic and at least one modifiable lifestyle attribute of the individual, the pangenetic attribute(s) further comprising genetic or epigenetic attributes;

iii) determining, based on a comparison of the attribute profile of the individual and the previously stored database of attribute profiles and disease data for the population of individuals, one or more modifiable lifestyle attributes associated with the individual, which provide a personalized treatment regimen for the disease; and

iv) transmitting the one or more modifiable lifestyle attributes as output to provide the recommended personalized treatment regimen for the disease for the individual.

2. The non-transitory computer readable medium of claim 1 , further comprising a set of instructions that, when executed by a processor, cause that processor to perform the step of:

v) rank ordering the one or more modifiable lifestyle attributes in an order corresponding to those modifiable attributes that provide the most effective recommended personalized treatment regimen for the disease.

3. A computer based method for generating a pangenetic based determination of one or more disease related modifiable lifestyle attributes for an individual, which when modified provide a recommended personalized treatment regimen for a disease, comprising:

a) receiving a query related to the individual and the disease;

b) accessing an attribute profile associated with the individual, the attribute profile comprising pangenetic attributes and at least one modifiable lifestyle attribute of the individual, the pangenetic attribute(s) further comprising genetic or epigenetic attributes;

c) accessing a previously stored database containing pangenetic and modifiable lifestyle attributes along with disease data for a population of individuals, wherein a portion of the pangenetic and modifiable lifestyle attributes are correlated with at least a portion of disease data, the pangenetic attribute(s) further comprising genetic or epigenetic attributes;

d) determining, by comparing the attribute profile of the individual and with attributes in the previously stored database containing pangenetic and modifiable lifestyle attributes correlated with disease data for the population of individuals, one or more modifiable lifestyle attributes that when modified provide a personalized treatment regimen for the disease; and

e) transmitting the one or more modifiable lifestyle attributes as output to provide a recommended personalized treatment regimen for the disease for the individual.

4. The computer based method of claim 3 , further comprising:

f) rank ordering the one or more modifiable lifestyle attributes in an order corresponding to those modifiable attributes that provide the most effective recommended personalized treatment regimen for the disease.

5. A system for generating a pangenetic based determination of one or more modifiable lifestyle attributes for an individual, which when modified provide a recommended personalized treatment regimen for a disease, comprising:

a) a previously stored database of attribute profiles and disease data for a population of individuals, wherein each attribute profile comprises pangenetic and modifiable lifestyle attributes correlated with at least a portion of the disease data the pangenetic attribute(s) further comprising genetic or epigenetic attributes; and

b) a processor and an associated memory, the associated memory containing a set of instructions that, when executed by a processor, cause the processor to perform the steps of:

i) receiving a query associated with an individual and the disease;

ii) accessing an attribute profile associated with the individual, wherein the attribute profile contains pangenetic and at least one modifiable lifestyle attribute of the individual, the pangenetic attribute(s) further comprising genetic or epigenetic attributes;

iii) determining, by comparing the attribute profile of the individual with attribute profiles and disease data in the previously stored database for the population of individuals, one or more modifiable lifestyle attributes associated with the individual which when modified provide a personalized treatment regimen for the disease; and

iv) transmitting the one or more modifiable lifestyle attributes as output to provide a recommended personalized treatment regimen for the disease of the individual.

6. The system of claim 5 , further comprising a set of instructions that, when executed by a processor, cause the processor to perform the step of:

v) rank ordering the one or more modifiable lifestyle attributes in an order corresponding to those modifiable attributes that provide the most effective recommended personalized treatment regimen for the disease of the individual.

Assignments (9)
CORRECTIVE ASSIGNMENT TO CORRECT THE APP. NO. 63806415 TO 63806145 AND APPL NO. 17721779 TO 17731779 PREVIOUSLY RECORDED ON REEL 73168 FRAME 531. ASSIGNOR(S) HEREBY CONFIRMS THE CHANGE OF NAME. Recorded Jan 6, 2026
From: 23ANDME PGS LLC
To: 23ANDME GENOMICS LLC
Reel/Frame 074434/0334 →
CHANGE OF NAME Recorded Oct 22, 2025
From: 23ANDME PGS LLC
To: 23ANDME GENOMICS LLC
Reel/Frame 073168/0531 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 26, 2025
From: 23ANDME, INC.
To: 23ANDME PGS LLC
Reel/Frame 072562/0795 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE ADDRESS PREVIOUSLY RECORDED AT REEL: 058554 FRAME: 0021. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT . Recorded Jan 7, 2022
From: EXPANSE BIOINFORMATICS, INC.
To: 23ANDME, INC.
Reel/Frame 058982/0739 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 5, 2022
From: EXPANSE BIOINFORMATICS, INC.
To: 23ANDME, INC.
Reel/Frame 058554/0021 →
CHANGE OF ADDRESS BY ASSIGNEE Recorded Apr 5, 2021
From: EXPANSE BIOINFORMATICS, INC.
To: EXPANSE BIOINFORMATICS, INC.
Reel/Frame 055823/0714 →
CHANGE OF NAME Recorded Sep 23, 2013
From: EXPANSE NETWORKS, INC.
To: EXPANSE BIOINFORMATICS, INC.
Reel/Frame 031289/0003 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 11, 2012
From: ELDERING, CHARLES A.
To: EXPANSE NETWORKS, INC.
Reel/Frame 028353/0216 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 11, 2012
From: KENEDY, ANDREW ALEXANDER
To: EXPANSE NETWORKS, INC.
Reel/Frame 028352/0619 →
Continuity (4)
Continuation 13079601 · Apr 4, 2011
Continuation 12048196 · Mar 13, 2008
Provisional Application 60895236 · Mar 16, 2007
Related Publication 20120221350A1 · Aug 30, 2012