PCan065 Antibody Compositions and Methods of Use
The invention provides isolated anti-PCan065 antibodies that bind to PCan065. The invention also encompasses compositions comprising an anti-PCan065 antibody and a carrier. These compositions can be provided in an article of manufacture or a kit. Another aspect of the invention is an isolated nucleic acid encoding an anti-PCan065 antibody, as well as an expression vector comprising the isolated nucleic acid. Also provided are cells that produce the anti-PCan065 antibodies. The invention encompasses a method of producing the anti-PCan065 antibodies. Other aspects of the invention are a method of killing an PCan065-expressing cancer cell, comprising contacting the cancer cell with an anti-PCan065 antibody and a method of alleviating or treating an PCan065-expressing cancer in a mammal, comprising administering a therapeutically effective amount of the anti-PCan065 antibody to the mammal.
1 - 78 . (canceled)
79 . A kit for detection and quantitation of PCan065 comprising an anti-PCan065 antibody, wherein PCan065 can be quantified in the range of about 0.015-6 ng/mL with the kit.
80 . The kit of claim 79 wherein the antibody is a polyclonal, monoclonal, humanized, or human antibody.
81 . The kit of claim 79 wherein the antibody is detectably labeled.
82 . The kit of claim 81 wherein the label is selected from the group comprising fluorescent, radio and enzymatic labels.
83 . The kit of claim 79 further comprising diluents or buffers.
84 . The kit of claim 79 further comprising a package insert.
85 . The kit of claim 84 wherein the package insert indicates the kit is used for detecting PCan065 levels.
86 . The kit of claim 84 wherein the package insert provides instructions for the intended in-vitro or diagnostic use of the kit.