IP Library Granted Patent US 8,815,270
Granted Patent B2
US 8,815,270 · App. 13/466,858 · Granted Aug 26, 2014

Methods and compositions for treating ectoparasite infestation

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Quick Facts
Patent No.
US 8,815,270
App. No.
13/466,858
Granted
Aug 26, 2014
Kind
B2
Abstract

Compositions and methods for killing ectoparasites on a subject. Compositions containing a fatty acid ester, e.g., isopropyl myristate, effective for killing ectoparasites is described. Also described are compositions containing a fatty acid ester and a siloxane (e.g., decacyclomethicone). The compositions can also contain a mectin and/or a mycin, and S-methoprene. The compositions are useful against a variety of ectoparasites that afflict humans, animals, and plants, e.g., head lice, fleas, body lice, crab lice, scabies, ticks, and plant parasites.

Claims (11)

1. A method of killing ectoparasites on a subject, said method comprising:

topically administering to an area on the subject where ectoparasites are present a composition consisting essentially of isopropyl palmitate at a concentration of at least 25% w/w and at least 20% cyclic siloxane;

further wherein said composition does not contain any other agent in an amount effective for killing said ectoparasites.

2. A method according to claim 1 , wherein said ectoparasites are selected from the group consisting of lice, mites, ticks, and fleas.

3. A method according to claim 2 , wherein the subject is a mammal.

4. A method according to claim 3 , wherein the mammal is a human and the ectoparasites are head lice.

5. A method according to claim 3 , wherein the mammal is a dog or cat and the ectoparasites are fleas or ticks.

6. A method according to claim 3 , wherein the mammal is a dog or cat and the ectoparasites are mites.

7. A method according to claim 3 , wherein said ectoparasite is selected from the group consisting of body lice, crab lice, scabies, and ticks.

8. A method according to claim 1 , wherein the cyclic siloxane is selected from the group consisting of decacyclomethicone, octametylcyclomethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, and decamethylcyclopentasiloxane.

9. A method according to claim 1 , wherein said cyclic siloxane is decacyclomethicone.

Assignments (6)
RELEASE OF SECURITY INTEREST Recorded Mar 14, 2023
From: DEERFIELD PRIVATE DESIGN FUND III, L.P., AS AGENT
To: NUVO PHARMACEUTICALS INC.; ARALEZ PHARMACEUTICALS CANADA INC.; NUVO PHARMACEUTICALS (IRELAND) DESIGNATED ACTIVITY COMPANY (F/K/A NUVO PHARMACEUTICALS (IRELAND) LIMITED)
Reel/Frame 062974/0236 →
CHANGE OF NAME Recorded Mar 31, 2020
From: NUVO PHARMACEUTICALS (IRELAND) LIMITED
To: NUVO PHARMACEUTICALS (IRELAND) DESIGNATED ACTIVITY COMPANY
Reel/Frame 052279/0604 →
SECURITY INTEREST Recorded Dec 31, 2018
From: NUVO PHARMACEUTICALS INC.; NUVO PHARMACEUTICALS (IRELAND) DESIGNATED ACTIVITY COMPANY; ARALEZ PHARMACEUTICALS CANADA INC.
To: DEERFIELD PRIVATE DESIGN FUND III, L.P., AS AGENT
Reel/Frame 047875/0410 →
RELEASE OF SECURITY INTEREST Recorded Feb 22, 2018
From: PINNACLE BANK (SUCCESSOR TO BANK OF NORTH CAROLINA)
To: PIEDMONT PHARMACEUTICALS LLC
Reel/Frame 045007/0895 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 22, 2018
From: PIEDMONT PHARMACEUTICALS LLC
To: NUVO PHARMACEUTICALS (IRELAND) LIMITED
Reel/Frame 045008/0404 →
SECURITY INTEREST Recorded Mar 30, 2017
From: PIEDMONT PHARMACEUTICALS LLC
To: BANK OF NORTH CAROLINA
Reel/Frame 041799/0592 →