IP Library Granted Patent US 8,501,196
Granted Patent B2
US 8,501,196 · App. 13/467,795 · Granted Aug 6, 2013

Pharmaceutical compositions containing botulinum neurotoxin

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Quick Facts
Patent No.
US 8,501,196
App. No.
13/467,795
Granted
Aug 6, 2013
Kind
B2
Abstract

This invention relates to the use of a composition comprising a polysaccharide and a botulinum toxin for reducing a skin wrinkle. In some embodiments, the polysaccharide comprises disaccharides. In some embodiments, the average molecular weight of a disaccharide unit of the polysaccharide is between about 345 D and about 1,000 D.

Claims (6)

1. A pharmaceutical composition comprising a collagen and a botulinum toxin, wherein the pharmaceutical composition is albumin free.

2. The pharmaceutical composition of claim 1 , wherein the botulinum toxin is selected from the group consisting of botulinum toxin types A, B, C 1 , D, E, F and G.

3. The pharmaceutical composition of claim 1 , wherein the pharmaceutical composition has a pH of between about 5 and 7.3 when reconstituted or upon injection.

4. The pharmaceutical composition of claim 1 , wherein the botulinum toxin comprises a botulinum toxin complex.

5. The pharmaceutical composition of claim 4 , wherein the botulinum toxin complex comprises a botulinum toxin complex type A.

6. The pharmaceutical composition of claim 4 , wherein the botulinum toxin complex comprises a botulinum toxin complex type B.