IP Library Granted Patent US 10,137,303
Granted Patent B2
US 10,137,303 · App. 13/473,470 · Granted Nov 27, 2018

Cortical interface for motor signal recording and sensory signal stimulation

Inventors: Robert J Greenberg (Los Angeles, CA); David Daomin Zhou (Valencia, CA); Brian V Mech (Santa Clarita, CA); Neil Hamilton Talbot (La Crescenta, CA); Rongqing Dai (Valencia, CA); Richard Agustin Castro (Santa Monica, CA); Kelly H. McClure (Simi Valley, CA)
Assignee: Second Sight Medical Products, Inc.
A61N1/36082A61B5/04001A61B5/4064A61N1/0531A61N1/0534A61N1/0539A61B5/6868A61N1/375H01L2224/05599H01L2224/45144H01L2224/48227H01L2224/48465H01L2224/85099H01L2224/85399H01L2924/3011H05K1/118H05K1/189H05K2201/0154H05K2201/10098
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Quick Facts
Patent No.
US 10,137,303
App. No.
13/473,470
Granted
Nov 27, 2018
Kind
B2
Abstract

The present invention consists of an implantable device with at least one package that houses electronics that sends and receives data or signals, and optionally power, from an external system through at least one coil attached to the at least one package and processes the data, including recordings of neural activity, and delivers electrical pulses to neural tissue through at least one array of multiple electrodes that is/are attached to the at least one package. The device is adapted to electrocorticographic (ECoG) and local field potential (LFP) signals. The output signals provide control for a motor prosthesis and the inputs signals provide sensory feedback for the motor prosthesis. The invention, or components thereof, is/are intended to be installed in the head, or on or in the cranium or on the dura, or on or in the brain.

Claims (50)

1. An implantation system comprising:

an implantable device comprising:

a hermetic package enclosing an electronic circuit suitable to be implanted within a head,

a flat flexible circuit, including a polymer base layer, conductive traces and a polymer top layer, and including a plurality of electrodes electrically coupled to the electronic circuit suitable to record neural activity, the flexible circuit forming a plurality of flexible fingers with electrodes disposed directly on each of the flexible fingers, each flexible finger including a tip at an opposite end of the flexible circuit from the hermetic package, and a flexible feature, defining a void, at the tip suitable to accept an implantation tool, and

a wireless transceiver electrically coupled to the electronic circuit for sending data derived from the neural activity and receiving sensory data; and

the implantation tool including a plurality of features configured to engage the voids in each of the fingers and press the plurality of fingers into tissue.

2. The implantation system according to claim 1 , where the electronic circuit is adapted to record electrocorticographic signals.

3. The implantation system according to claim 1 , wherein the electronic circuit is adapted to record local field potential signals.

4. The implantation system according to claim 1 , wherein the data controls a motor prosthesis.

5. The implantation system according to claim 1 , wherein the plurality of electrodes are part of a flexible circuit electrode array bonded to the hermetic package.

6. An implantation system comprising:

a flexible circuit electrode array with integrated array cable adapted for neural stimulation comprising:

a polymer base layer forming an array portion and a cable portion, the cable portion adapted to connect to an electronic circuit and the array portion forming a plurality of separate flexible fingers, each flexible finger including a tip at an opposite end of the array from the electronic circuit, and a flexible feature at the tip, forming a void, suitable to accept an implantation tool,

patterned metal traces deposited on said polymer base layer, including electrodes deposited directly on the flexible fingers,

a polymer top layer deposited on said polymer base layer and said polymer top layer defining voids for electrodes,

wherein at least some electrode surfaces are in different planes, and

the implantation tool including a plurality of features configured to engage the voids in each of the fingers and press the plurality of fingers into tissue.

7. The implantation system according to claim 6 , wherein at least some of the fingers are curved.

8. The implantation system according to claim 6 , wherein at least some of the fingers are pointed.

9. The implantation system according to claim 6 , wherein the voids include plated electrodes.

10. The implantation system according to claim 9 , wherein the plated electrodes have a fractal surface.

11. An implantation system comprising:

a neural interface comprising:

a hermetic package enclosing an electronic circuit suitable to be implanted within a head,

a wireless transceiver electrically coupled to the electronic circuit for sending data derived from neural activity and receiving sensory data, and

a flexible electrode array including

a polymer base layer forming an array portion and a cable portion, the cable portion adapted to connect to an electronic circuit and the array portion forming a plurality of separate flexible fingers, each flexible finger including a tip at an opposite end of the array from the hermetic package and a flexible feature at the tip, defining a void, suitable to accept an implantation tool,

patterned metal traces deposited on said polymer base layer, including electrodes deposited directly on the flexible fingers,

a polymer top layer deposited on said polymer base layer and said metal traces defining voids for electrodes; and

the implantation tool including a plurality of features configured to engage the voids in each of the fingers and press the plurality of fingers into tissue.

12. The implantation system according to claim 11 , wherein said electrode array includes more than 50 electrodes.

13. The implantation system according to claim 11 , wherein said electrode array includes more than 75 electrodes.

14. The implantation system according to claim 11 , wherein said electrode array includes more than 100 electrodes.

15. The implantation system according to claim 11 , wherein said electrode array includes more than 200 electrodes.

16. The implantation system according to claim 11 , further comprising a plurality of thin film electrode arrays electrically coupled to the electronics.

17. The implantation system according to claim 11 , wherein the hermetic package is suitable to be attached to tissue.

18. The implantation system according to claim 17 , wherein the tissue is a dura.

19. The implantation system according to claim 17 , wherein the tissue is a cranium.

20. The implantation system according to claim 17 , wherein the tissue is a scalp.

21. An implantation system comprising:

a flexible circuit electrode array with integrated array cable adapted for neural stimulation comprising:

a polymer base layer forming an array portion and a cable portion, the cable portion adapted to connect to an electronic circuit and the array portion forming a plurality of separate flat flexible fingers,

patterned metal traces deposited on said polymer base layer, including electrodes deposited directly on the flexible fingers;

a polymer top layer deposited on said polymer base layer and said polymer top layer defining voids for electrodes;

wherein the fingers include a tip at an opposite end of the array from the electronic circuit and define voids at the tip suitable to accept an implantation tool;

the implantation tool including a plurality of features configured to engage the voids in each of the fingers and press the plurality of fingers into tissue.

22. The implantation system according to claim 21 , wherein at least some of the fingers are curved.

23. The implantation system according to claim 21 , wherein at least some of the fingers are pointed.

24. The implantation system according to claim 21 , wherein the voids include plated electrodes.

25. The implantation system according to claim 21 , wherein the plated electrodes have a fractal surface.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 28, 2023
From: GREENBERG, ROBERT J; ZHOU, DAVID DAOMIN; MECH, BRIAN V; TALBOT, NEIL; DAI, RONGQING; CASTRO, RICHARD; MCCLURE, KELLY H
To: SECOND SIGHT MEDICAL PRODUCTS, INC.
Reel/Frame 062890/0069 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 3, 2023
From: VIVANI MEDICAL, INC.
To: CORTIGENT, INC.
Reel/Frame 062589/0523 →
MERGER AND CHANGE OF NAME Recorded Dec 27, 2022
From: SECOND SIGHT MEDICAL PRODUCTS, INC.; VIVANI MEDICAL, INC.
To: VIVANI MEDICAL, INC.
Reel/Frame 062230/0479 →
Continuity (2)
Provisional Application 61486704 · May 16, 2011
Related Publication 20120296444A1 · Nov 22, 2012
Cited By (4)
US 12,344,566 US 12,539,083 US 12,653,064 US 12,679,783