High-frequency electrical nerve block
A method and apparatus that resulted in blocking an action potential in a nerve.
1. A method of ameliorating sensory nerve pain in a patient in need thereof, the method comprising
(a) connecting a waveform generator operatively to an implanted electrode contacting a trunk of a sensory peripheral nerve having a diameter exceeding 3 mm and up to 12 mm in the patient, resulting in prevention of action potential transmission in the nerve upon application of a waveform of at least 5 kHz up to 50 kHz where the frequency blocks but does not stimulate and is not used to generate an action potential in a nerve but rather to block conduction of an action potential at one of a voltage ranging from 4 Vpp to 20 Vpp, or a current ranging from 4 mApp to 26 mApp at a plurality of contact surfaces with the nerve trunk for an interval sufficient to effect substantially immediate pain relief in the patient, and
(b) optionally repeating step (a) as needed to ameliorate nerve pain.
2. The method of claim 1 where the waveform provided is a sinusoidal waveform at 10 kHz.
3. The method of claim 1 where the nerve is a sciatic nerve.
4. The method of claim 1 where the nerve is a tibial nerve.
5. The method of claim 1 where the interval is controlled by the patient.
6. The method of claim 1 where step (a) uses a mono-, bi-, or tri-polar electrode contacting the affected nerve and contained in a cuff.
7. The method of claim 6 wherein the cuff has an inner diameter ranging from about 5 mm to about 12 mm.
8. The method of claim 1 wherein the interval is about 10 minutes.
9. The method of claim 1 where the current or voltage provided increases magnitude ranging from about 10 seconds to about 60 seconds with a steady ramp up.
10. The method of claim 1 where the electrode has a relatively larger contact surface with the nerve than conventional electrodes.
11. The method of claim 1 resulting in ameliorated amputation pain.
12. A method for reversibly blocking an action potential in a sensory nerve of a patient to effect a desired response in the patient, the method comprising
(a) connecting a waveform generator operatively to an implanted electrode contacting a trunk of the sensory nerve in the patient, resulting in prevention of action potential transmission in the nerve upon application of a waveform of at least 5 kHz up to 50 kHz where the frequency blocks but does not stimulate and is not used to generate an action potential in a nerve but rather to block conduction of an action potential at one of a voltage ranging from 4 Vpp to 20 Vpp, or a current ranging from 4 mApp to 26 mApp, to the nerve trunk for an interval sufficient to effect a substantially immediate response in the patient, and
(b) optionally repeating step (a).
13. The method of claim 12 where the response is pain relief and the patient experiences pain relief substantially immediately upon application of the electrical waveform.
14. The method of claim 12 where the response is ameliorating spasticity of a muscle enervated by the nerve and the patient experiences spasticity amelioration substantially immediately upon application of the electrical waveform.
15. The method of claim 12 where the response is ameliorating an urge to void a bladder and the patient experiences urge amelioration substantially immediately upon application of the electrical waveform.
16. The method of claim 12 where the waveform provided is a sinusoidal waveform.