Accommodative intraocular lens and method of implantation
View Patent ↗An accommodating intraocular lens (AIOL) adapted for implantation into a capsular bag includes an outer shell, a valve, and a force transfer assembly. The outer shell includes at least one surface modification on at least a periphery of the outer shell to promote bonding with the capsular bag. The valve is configured to permit injection of a fill material. The force transfer assembly in the outer shell is adapted to transfer forces from the capsular bag to change the shape of the filled outer shell in response to changes in capsular bag shape.
1. An accommodating intraocular lens (AIOL) adapted for implantation into a capsular bag, comprising:
an outer shell comprising an anterior segment and a posterior segment connected at a living hinge at a periphery of the AIOL, the anterior segment and posterior segment defining an internal void that is fillable with a fill material such that a portion of a periphery of the outer shell expands to directly contact a capsular bag, the outer shell including at least one surface modification at a contact region on at least the portion of the periphery of the outer shell, the surface modification configured to promote growth and adhesion of epithelial cells such that the capsular bag is adhered to the outer shell at the contact region, wherein the outer shell is adapted such that the capsular bag exerts force on the outer shell at the contact region when adhered to the outer shell;
a fill material;
a valve configured to permit injection of the fill material;
at least one sharp peripheral edge shaped to hold the capsular bag to reduce posterior capsule opacification; and
a force transfer assembly comprising at least one stiffening rib, the at least one stiffening rib comprising a region of the anterior segment of the outer shell having a greater thickness than adjacent regions of the anterior segment of the outer shell and extending into the internal void only a portion of the way between the anterior segment and the posterior segment, the force transfer assembly adapted to transfer the forces from the capsular bag at the contact region to change the shape of the filled outer shell in response to changes in capsular bag shape,
wherein the living hinge is configured such that a void is maintained between the living hinge and the capsular bag,
wherein the at least one surface modification comprises one or more of nano-texturing, a surface coating, and a biocompatible adhesive.
2. The AIOL of claim 1 , wherein the fill material comprises a polymer gel.
3. The AIOL of claim 1 , wherein the outer shell further comprises a peripheral band and wherein the at least one surface modification is on the peripheral band.
4. The AIOL of claim 1 , wherein the surface coating comprises one or more of complementary proteins, growth factors for the capsular bag, and chitin.