IP Library › Granted Patent US 8,754,092
Granted Patent B2
US 8,754,092 · App. 13/487,594 · Granted Jun 17, 2014

Inhibitors of the hedgehog pathway

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Quick Facts
Patent No.
US 8,754,092
App. No.
13/487,594
Granted
Jun 17, 2014
Kind
B2
Abstract

The present invention is directed to a compound of Formula I or a single isomer thereof; where the compound is optionally as a pharmaceutically acceptable salt, hydrate, solvate or combination thereof, in addition to methods of preparing a Compound of Formula I, and methods of using a Compound of Formula I to treat cancer.

Claims (2)

1. A method of treating leukemia, comprising administering to a patient in need thereof a therapeutically effective amount of N-{2-methyl-5-[(methylamino)methyl]phenyl}-4-[(4-phenylquinazolin-2-yl)amino]benzamide, having the structure

optionally as a pharmaceutically acceptable salt thereof, and optionally with a pharmaceutically acceptable carrier, excipient, or diluent.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 27, 2022
From: EXELIXIS PATENT COMPANY LLC
To: EXELIXIS, INC.
Reel/Frame 059752/0813 →