Methods for evaluating the integrity of a uterine cavity
View Patent ↗Methods, systems and devices for evaluating the integrity of a uterine cavity. A method comprises introducing transcervically a probe into a patient's uterine cavity, providing a flow of a fluid (e.g., CO 2 ) through the probe into the uterine cavity and monitoring the rate of the flow to characterize the uterine cavity as perforated or non-perforated based on a change in the flow rate.
1. A method for treatment of uterine tissue, comprising:
positioning an expandable structure in a patient's uterine cavity, the expandable structure comprising a portion of an energy application system for delivering ablation energy to uterine tissue;
expanding the expandable structure to occupy a substantial volume of the patient's uterine cavity;
introducing a gas into the uterine cavity exterior of the expandable structure;
introducing a gas into the expandable structure as the expandable structure expands;
monitoring a parameter of the gas introduced into the expandable structure as the expandable structure expands to determine whether the uterine cavity is perforated or non-perforated; and
monitoring a parameter of the gas introduced into the uterine cavity exterior of the expandable structure as the expandable structure expands to determine whether the uterine cavity is perforated or non-perforated,
wherein the parameter of the gas introduced into the uterine cavity is gas volume, and
wherein the monitoring of the parameter of the gas introduced into the uterine cavity exterior of the expandable structure as the expandable structure expands to determine whether the uterine cavity is perforated or non-perforated comprises determining that the uterine cavity is perforated if the gas volume is less than a first threshold volume after a predetermined period of time.
2. The method of claim 1 , wherein the positioning step comprises transcervically introducing an elongated member into the uterine cavity, the elongated member carrying the expandable structure.
3. The method of claim 1 , wherein the positioning step includes expanding the expandable structure with at least one of a frame and gas pressure.
4. The method of claim 1 wherein an additional monitored parameter of the gas introduced into the expandable structure or the uterine cavity is a gas flow rate or change in gas flow rate.
5. The method of claim 4 , wherein the uterine cavity is determined as perforated if the gas flow rate into the expandable structure or the uterine cavity meets a predetermined decay.
6. The method of claim 5 , wherein the gas flow rate into the expandable structure or the uterine cavity meets a predetermined decay if the gas flow rate drops below a predetermined minimum threshold rate within the predetermined period of time.
7. The method of claim 1 wherein an additional monitored parameter of the gas introduced into the expandable structure or the uterine cavity is gas pressure.
8. The method of claim 7 , wherein the uterine cavity is determined as perforated if the gas pressure in the expandable structure and the gas pressure in the uterine cavity reach an equilibrium.
9. The method of claim 1 wherein the parameter of the gas introduced into the expandable structure is gas volume.
10. The method of claim 9 , further comprising determining that the uterine cavity is perforated if the gas volume of the gas introduced into the expandable structure is less than a second threshold volume.
11. The method of claim 1 wherein the parameter of the gas introduced into the expandable structure and the parameter of the gas introduced into the uterine cavity are monitored contemporaneously.
12. The method of claim 1 wherein the parameter of the gas introduced into the expandable structure and the parameter of the gas introduced into the uterine cavity are monitored sequentially.
13. The method of claim 1 wherein the parameter of the gas introduced into the uterine cavity is monitored first and then the parameter of the gas introduced into the expandable structure is monitored.
14. The method of claim 1 wherein the parameter of the gas introduced into the expandable structure is monitored first and then the parameter of the gas introduced into the uterine cavity is monitored.
15. The method of claim 1 wherein monitoring the parameter of the gas introduced into the uterine cavity exterior of the expandable structure includes monitoring the parameter of the gas introduced into the uterine cavity at least twice.
16. The method of claim 1 wherein monitoring the parameter of the gas introduced into the expandable structure includes monitoring the parameter of the gas introduced into the expandable structure at least twice.
17. The method of claim 1 further comprising delivering the ablation energy to the uterine tissue when the monitoring step of monitoring the parameter of the gas introduced into the uterine cavity exterior of the expandable structure indicates that the uterine cavity is non-perforated.
18. The method of claim 1 further comprising automatically activating the energy application system to deliver ablation energy to the uterine tissue when both of the monitoring steps determine that the uterine cavity is non-perforated.
19. The method of claim 1 , wherein the predetermined period of time is in the range from 1 second to 60 seconds.