Sintered porous plastic liquid barrier media and applications thereof
View Patent ↗This application discloses porous self-sealing media comprising a sintered mixture of an absorbent material and a thermoplastic. The self-sealing media block passage of organic solvents or organic solvents in aqueous mixtures, wherein the organic solvents are at concentrations greater than about 40%. The self-sealing media also block acidic solutions. The self-sealing media are useful in a variety of applications such as a pipette tip filter, in line filter, vent, non-mechanical check valve, safety valve, and suction canister.
1. A porous self-sealing composition comprising a sintered porous matrix of particles of an absorbent material and particles of a thermoplastic, wherein the absorbent material comprises polyacrylic acid, and the polyacrylic acid is linear polyacrylic acid with a molecular weight greater than 100 KDa or cross-linked polyacrylic acid with a linear backbone molecular weight between adjacent crosslinks (Mc) greater than 10 KDa.
2. The composition of claim 1 , wherein the absorbent material in the sintered porous matrix is from about 1% to about 45%, from about 3% to about 40%, from about 5% to about 35%, or from about 10% to about 30%, by weight of the sintered porous matrix.
3. The composition of claim 1 , wherein the sintered porous matrix has a porosity of from about 10% to about 70%, from about 20% to about 60%, or from about 30% to about 50%.
4. The composition of claim 1 , wherein the sintered porous matrix has an average pore size of from about 1 micron to about 200 microns, from about 5 microns to about 100 microns, or from about 10 microns to about 50 microns.
5. The composition of claim 1 , wherein the cross-linked polyacrylic acid has a cross-linking density of less than about 0.5%, less than about 0.2% or less than about 0.1%.
6. The composition of claim 1 , wherein the thermoplastic particles are selected from the group consisting of polyethylene, polypropylene and polyvinylidene fluoride (PVDF).
7. The composition of claim 6 , wherein the polyethylene is high density polyethylene (HDPE), low density polyethylene (LDPE), very high molecular weight polyethylene (VHMWPE), or ultrahigh molecular weight polyethylene (UHMWPE).
8. The composition of claim 1 , further comprising a thermoplastic elastomer or a color change indicator.
9. The composition of claim 1 , further comprising an absorbent material, CMC or a superabsorbent material.
10. A device comprising the composition of claim 1 .
11. The device of claim 10 , wherein the device is a pipette tip, an in line filter, a vent, a valve, a container, a non-mechanical check valve, a safety valve, a syringe cap, or a suction canister.
12. A method of making the composition claim 1 comprising:
providing particles of polyacrylic acid, wherein the polyacrylic acid is linear polyacrylic with a molecular weight greater than 100 KDa or cross-linked polyacrylic with a the linear backbone molecular weight between adjacent crosslinks (Mc) greater than 10 KDa;
providing particles of a thermoplastic;
blending the particles of polyacrylic acid and the particles of thermoplastic to make a mixture;
adding the mixture to a mold;
sintering the mixture;
removing the mixture from the mold.
13. A method of blocking the passage of a solution comprising:
contacting the composition of claim 1 with the solution; and,
permitting the composition to absorb the solution and seal, whereby passage of the solution is blocked by the composition.
14. The method of claim 13 , wherein the solution comprises an organic solvent or an aqueous solution of more than 40% of an organic solvent.
15. The method of claim 13 , wherein the solution comprises more than 5% of an inorganic acid or more than 5% of an organic acid.
16. The method of claim 13 , wherein the contacting step occurs at about 2 psi.
17. The method of claim 13 , wherein the solution further comprises a surfactant.