IP Library Granted Patent US 9,040,747
Granted Patent B2
US 9,040,747 · App. 13/501,692 · Granted May 26, 2015

Method for producing reduced coenzyme Q10, method for stabilizing same, and composition comprising same

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Quick Facts
Patent No.
US 9,040,747
App. No.
13/501,692
Granted
May 26, 2015
Kind
B2
Abstract

An object of the present invention is to provide a substance characterized by ability to reduce oxidized coenzyme Q10 and ability to stabilize reduced coenzyme Q10, which contains nutrients, has a favorable taste, and is excellent in general versatility, and a method for using the same. The present invention relates to a method for producing reduced coenzyme Q10 comprising reducing oxidized coenzyme Q10 with a particular amino acid. The present invention also relates to a method for stabilizing reduced coenzyme Q10 in the presence of a particular amino acid and a composition stabilized by the method.

Claims (7)

1. A method for producing reduced coenzyme Q10 which comprises reducing oxidized coenzyme Q10 at a reaction temperature or 50° C. or more using an amino acid with a side chain containing a functional group comprising a nitrogen atom and/or an oxygen atom, wherein the amino acid is lysine.

2. The production method of claim 1 , wherein the reduction reaction is carried out in the presence of an organic solvent, a fat, an oil, water, or a mixture thereof.

3. The production method of claim 2 , wherein the organic solvent is at least one member selected from the group consisting of alcohols, fatty acids, and terpenes.

4. The production method of claim 1 , wherein the reduction reaction is allowed to take place in a preparation selected from the group consisting of capsules, tablets, syrups, and dosage form for oral administration.

5. The production method of claim 4 , wherein the preparation is in the form of a capsule.

6. The production method of claim 1 , wherein the reduction reaction is carried out under a deoxygenated atmosphere.

7. The production method of claim 1 , wherein the reduction reaction is carried out in the presence of a solvent selected from the group consisting of alcohols, terpenes, plant fats and oils, medium-chain triglycerides (MCT) and mixtures thereof.

Assignments (3)
CHANGE OF ADDRESS Recorded Sep 12, 2013
From: KANEKA CORPORATION
To: KANEKA CORPORATION
Reel/Frame 031207/0283 →
CORRECTIVE ASSIGNMENT TO CORRECT THE AN ERROR IN THE TITLE, WHEREIN "STABLIZING" SHOULD READ --STABILIZING-- PREVIOUSLY RECORDED ON REEL 028038 FRAME 0181. ASSIGNOR(S) HEREBY CONFIRMS THE TITLE SHOULD BE CORRECTED.. Recorded Nov 15, 2012
From: JIKIHARA, TAKAAKI; YAMAGUCHI, TAKAO; KITAMURA, SHIRO; UEDA, YASUYOSHI
To: KANEKA CORPORATION
Reel/Frame 029309/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 12, 2012
From: JIKIHARA, TAKAAKI; YAMAGUCHI, TAKAO; KITAMURA, SHIRO; UEDA, YASUYOSHI
To: KANEKA CORPORATION
Reel/Frame 028038/0181 →