Matrix composition for delivery of hydrophobic actives
View Patent ↗A matrix composition capable of forming an emulsion/micro-emulsion comprising an emulsifiable matrix, essentially free of alkyl pyrrolidone and alkoxylated alcohol, comprising: (i) a long chain substituted amide; (ii) a surface active agent; and (iii) optionally, an organic diluent.
1. A matrix composition capable of forming an emulsion, a microemulsion, or a dispersion comprising an emulsifiable matrix, consisting of:
(i) a dialkyl acid amide having the formula:
wherein,
R 1 and R 2 are lower alkyl with 1-4 carbon atoms, alicyclic or aromatic;
n 1 =0-18, n 2 =0-18, and R═H or CH 3 ; and
(ii) one or more surface active agents, wherein the only surface active agents present are selected from the group consisting of ethoxylated castor oil, ethoxylated/propoxylated block copolymer, ethoxylated phosphate ester, sodium dioctyl sulfosuccinate, and poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol), and wherein at least one of the surface active agents is ethoxylated castor oil.
2. The matrix composition according to claim 1 , wherein R 1 ═R 2 ═CH 3 ; R═H; n 2 =0 and n 1 =5-11.
3. The matrix composition according to claim 2 , wherein R1=R2=CH 3 ; R═H; n 2 =0 and n 1 =7-9.
4. The matrix composition according to claim 1 , wherein the dialkyl acid amide is selected from the group consisting of N,N-dimethyl hexamide, N,N-dimethyl octanamide, N,N-dimethyl decanamide, N,N-dimethyl dodecanamide, and N,N-dimethyl tetradecanamide.
5. The matrix composition according to claim 1 having, by weight:
1-99% of the dialkyl acid amide; and
1-99% of the surface active agents, and
wherein at least one of the surface active agents is ethoxylated/propoxylated block copolymer.
6. The matrix composition according to claim 5 , wherein the dialkyl acid amide is N, N-dimethyl octanamide, and the surface active agents are sodium dioctyl sulfosuccinate, ethoxylated/propoxylated block copolymer, and the ethoxylated castor oil.