IP Library Granted Patent US 8,489,192
Granted Patent B1
US 8,489,192 · App. 13/523,223 · Granted Jul 16, 2013

System and method for bronchial dilation

Inventors: Edwin J. Hlavka (Minneapolis, MN); Lynn Elliott (Maple Grove, MN)
Assignee: Holaira, Inc.
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 8,489,192
App. No.
13/523,223
Granted
Jul 16, 2013
Kind
B1
Abstract

A method of reducing bronchial constriction in a subject includes delivering energy to create one or more lesions on a main bronchus so as to transect pulmonary nerves sufficiently to reduce bronchial constriction in a lung of the patient distal to the main bronchus.

Claims (18)

1. A method of reducing bronchial constriction in a subject, comprising:

surgically transecting pulmonary nerves located along an airway in the subject sufficiently to reduce bronchial constriction in a lung of the patient; and

preventing re-innervation of the pulmonary nerves.

2. The method of claim 1 , wherein the preventing re-innervation of the pulmonary nerves includes transecting the pulmonary nerves of the subject at a plurality of locations by creating a series of lesions.

3. The method of claim 2 , wherein the plurality of locations are positioned around at least a portion of a circumference the airway of the subject.

4. The method of claim 2 , wherein transecting the pulmonary nerves includes transecting the pulmonary nerves using electrocautery.

5. The method of claim 2 , wherein the series of lesions includes two or more lesions separated by 2 mm to 15 mm gaps.

6. The method of claim 2 , wherein the series of lesions are linear.

7. The method of claim 1 , wherein preventing re-innervation of the pulmonary nerves includes attaching an implant on the bronchus to prevent the damaged nerves from reinnervating.

8. The method of claim 7 , wherein the implant includes a bioactive component that suppresses neuron growth or regeneration.

9. The method of claim 1 , wherein preventing re-innervation of the pulmonary nerves includes implanting an active stimulation system that substantially inhibits nerve signals at the airway to block both outgoing and incoming signals from the lungs to maintain the reduced bronchial constriction in the lung of the patient.

10. A method of reducing bronchial constriction in a subject, comprising:

surgically transecting pulmonary nerves using electrocautery, the surgically transecting pulmonary nerves including creating one or more lesions on a main bronchus so as to transect the pulmonary nerves sufficiently to reduce bronchial constriction in a lung of the patient distal to the main bronchus.

11. The method of claim 10 , wherein the lesions are created around the circumference of the main bronchus.

12. The method of claim 10 , wherein the lesions are created on an outer aspect of the main bronchus.

13. The method of claim 12 , wherein the outer aspect of the main bronchus is an anterior aspect of the main bronchus.

14. The method of claim 12 , wherein the outer aspect of the main bronchus is a posterior aspect of the main bronchus.

15. The method of claim 10 , wherein the pulmonary nerves follow the branching of a bronchial tree in a lung of the subject.

Assignments (6)
SECURITY INTEREST Recorded Oct 16, 2024
From: NUVAIRA, INC.
To: INNOVATUS LIFE SCIENCES LENDING FUND 1, LP
Reel/Frame 069175/0918 →
SECURITY INTEREST Recorded Dec 21, 2021
From: NUVAIRA, INC.
To: INNOVATUS LIFE SCIENCES LENDING FUND 1, LP
Reel/Frame 058561/0979 →
CHANGE OF NAME Recorded Jun 20, 2017
From: HOLAIRA, INC.
To: NUVAIRA, INC.
Reel/Frame 042915/0068 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 10, 2013
From: HLAVKA, EDWIN J.; ELLIOT, LYNN
To: CONCEPTX MEDICAL, INC.
Reel/Frame 031383/0528 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 10, 2013
From: CONCEPTX MEDICAL, INC.
To: INNOVATIVE PULMONARY SOLUTIONS, INC.
Reel/Frame 031383/0884 →
CHANGE OF NAME Recorded Feb 6, 2013
From: INNOVATIVE PULMONARY SOLUTIONS, INC.
To: HOLAIRA, INC.
Reel/Frame 029768/0930 →
Continuity (3)
Continuation 12372607 · Feb 17, 2009
Provisional Application 61049605 · May 1, 2008
Provisional Application 61066026 · Feb 15, 2008