Left atrial appendage treatment systems and methods
View Patent ↗Embodiments of the present invention encompass systems and methods to prevent complications from atrial fibrillation by preventing or reducing the likelihood of blood flow out of the left atrial appendage, to eliminate a possible source of aberrant electrical circuits, or both. Accordingly, techniques are provided for delivering ligature loops or closure means to the left atrial appendage, and to other anatomical structures of a patient which may be desirable in other surgical procedures.
1. A ligature delivery system for use with a left atrial appendage ligature assembly, the ligature delivery system comprising:
a thread delivery mechanism comprising a cinchable loop that receives a thread of the ligature assembly and that rotates axially about a central longitudinal axis between a first configuration whereby the thread is shielded from a left atrial appendage of a patient and a second configuration whereby the thread can be released onto the left atrial appendage;
a delivery control mechanism that cinches the loop about the left atrial appendage and that switches the loop between the first and second configurations, wherein the delivery control mechanism comprises a first rotary drive coupled with a first section of the cinchable loop and a second rotary drive coupled with a second section of the cinchable loop, such that applied torque is transmitted between the first and second rotary drives to rotate the cinchable loop;
a support mechanism having a first engagement assembly that receives a carrier of the ligature assembly, and a second engagement assembly coupled with the delivery control mechanism;
a deflector mechanism that pivots relative to the support mechanism and that is coupled with the loop; and
a deflection control mechanism having an actuation assembly and a linkage assembly, wherein the linkage assembly is coupled with the actuation assembly and the deflector mechanism, such that movement of the actuation assembly relative to the support mechanism causes the deflector body and loop to pivot relative to the support mechanism.
2. The system according to claim 1 , wherein the cinchable loop comprises a flexible cylinder having a longitudinally extending slot that receives the thread.
3. The system according to claim 1 , wherein the cinchable loop comprises a first section that translates longitudinally relative to a first guide of the deflector mechanism, and a second section that is translationally fixed relative to a second guide of the deflector mechanism.
4. The system according to claim 1 , wherein the delivery control mechanism effects coordinated axial rotation between a first end portion of the delivery mechanism and a second end portion of the delivery mechanism, the first and second end portions bounding a central portion of the loop.
5. The system according to claim 4 , wherein the delivery control mechanism comprises a gearbox assembly in operative association with the first and second end portions, the gearbox effecting the coordinated axial rotation.
6. The system according to claim 1 , wherein rotation of the first rotary drive drives counter-rotation of the second rotary drive and the rotating drives coordinate to switch the cinchable loop from the first configuration to the second configuration.
7. The system according to claim 1 , wherein the second engagement assembly comprises a first lumen, wherein the first rotary drive is disposed within the first lumen and coupled with a first section of the cinchable loop, wherein the first rotary drive is rotatable and translatable within the first lumen.
8. A ligature delivery system for use with a left atrial appendage ligature assembly, the ligature delivery system comprising:
a thread delivery mechanism comprising a cinchable loop that receives a thread of the ligature assembly and that rotates axially about a central longitudinal axis between a first configuration whereby the thread is shielded from a left atrial appendage of a patient and a second configuration whereby the thread can be released onto the left atrial appendage;
a delivery control mechanism that cinches the loop about the left atrial appendage and that switches the loop between the first and second configurations;
a support mechanism having a first engagement assembly that receives a carrier of the ligature assembly, and a second engagement assembly coupled with the delivery control mechanism, wherein the second engagement assembly comprises a first lumen and a second lumen;
a deflector mechanism that pivots relative to the support mechanism and that is coupled with the loop; and
a deflection control mechanism having an actuation assembly and a linkage assembly, wherein the linkage assembly is coupled with the actuation assembly and the deflector mechanism, such that movement of the actuation assembly relative to the support mechanism causes the deflector body and loop to pivot relative to the support mechanism, wherein the delivery control mechanism comprises a first rotary drive disposed within the first lumen and coupled with a first section of the cinchable loop and a second rotary drive disposed within the second lumen and coupled with a second section of the cinchable loop, wherein the first rotary drive is rotatable and translatable within the first lumen, and wherein the second rotary drive is rotatable within the second lumen.
9. The system according to claim 8 , wherein the cinchable loop comprises a flexible cylinder having a longitudinally extending slot that receives the thread.
10. The system according to claim 8 , wherein the cinchable loop comprises a first section that translates longitudinally relative to a first guide of the deflector mechanism, and a second section that is translationally fixed relative to a second guide of the deflector mechanism.
11. The system according to claim 8 , wherein the delivery control mechanism effects coordinated axial rotation between a first end portion of the delivery mechanism and a second end portion of the delivery mechanism, the first and second end portions bounding a central portion of the loop.
12. The system according to claim 11 , wherein the delivery control mechanism comprises a gearbox assembly in operative association with the first and second end portions, the gearbox effecting the coordinated axial rotation.
13. The system according to claim new 8 , wherein applied torque is transmitted between the first and second rotary drives to rotate the cinchable loop.
14. The system according to claim new 8 , wherein rotation of the first rotary drive drives counter-rotation of the second rotary drive and the rotating drives coordinate to switch the cinchable loop from the first configuration to the second configuration.
15. The system according to claim new 8 , wherein the second rotary drive does not translate within the second lumen.