IP Library Granted Patent US 8,663,477
Granted Patent B2
US 8,663,477 · App. 13/528,973 · Granted Mar 4, 2014

Chromatography column stand

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Quick Facts
Patent No.
US 8,663,477
App. No.
13/528,973
Granted
Mar 4, 2014
Kind
B2
Abstract

A method for conducting maintenance on a chromatography column ( 1; 51 ), said column comprising a column tube ( 32 ), a top end cell ( 20 ) and a bottom end cell ( 26 ), where during chromatography said column tube ( 32 ) is secured between said top end cell ( 20 ) and said bottom end cell ( 26 ). Said method comprises the step of rotating at least the top end cell ( 20 ) 180 degrees around a horizontal axis before maintenance is conducted to the top end cell ( 20 ).

Claims (29)

1. A method for conducting maintenance on a chromatography column ( 1 ; 51 ), said column comprising a column tube ( 32 ), a top end cell ( 20 ) and a bottom end cell ( 26 ), where during chromatography said column tube ( 32 ) is secured between said top end cell ( 20 ) and said bottom end cell ( 26 ), said method comprising the step of rotating, in situ, at least the top end cell ( 20 ) 180 degrees around a horizontal axis before maintenance is conducted to the top end cell ( 20 ).

2. The method for conducting maintenance on the chromatography column ( 1 ) of claim 1 , wherein said top end cell ( 20 ) being secured to rotatable upper fastening means ( 12 ) on a stand ( 2 ), said method comprising the steps of:

a) releasing the bottom end cell ( 26 ) and the column tube ( 32 ) from the top end cell ( 20 );

b) lowering the bottom end cell ( 26 ) and the column tube ( 32 );

c) rotating the top end cell ( 20 ) 180 degrees around a horizontal axis; and

d) conducting maintenance to the top end cell ( 20 ).

3. The method of claim 2 , further comprising the steps of:

a) removing the column tube ( 32 ); and

b) conducting maintenance to the bottom end cell ( 26 ).

4. The method of claim 3 , further comprising raising the bottom end cell ( 26 ) before conducting maintenance to it.

5. The method of claim 3 , further comprising rotating the bottom end cell ( 26 ) during the maintenance.

6. The method of claim 1 , wherein said chromatography column ( 51 ) is secured to rotatable upper fastening means ( 12 ) on a stand ( 2 ), said method comprising the steps of:

a) releasing the bottom end cell ( 26 ) from the top end cell ( 20 ) and the column tube ( 32 );

b) lowering the bottom end cell ( 26 );

c) conducting maintenance to the bottom end cell ( 26 );

d) raising the bottom end cell ( 26 ) and securing it to the column tube ( 32 ) and the top end cell ( 20 );

e) rotating the chromatography column ( 51 ) 180 degrees around a horizontal axis;

f) releasing the top end cell ( 20 ) from the bottom end cell ( 26 ) and the column tube ( 32 );

g) lowering the top end cell ( 20 ); and

h) conducting maintenance to the top end cell ( 20 ).

7. The method for conducting maintenance on the chromatography column ( 1 ) of claim 1 , wherein said top end cell ( 20 ) being secured to rotatable upper fastening means ( 12 ) on a stand ( 2 ), said method comprising the steps of:

a) releasing the bottom end cell ( 26 ) from the top end cell ( 20 ) and the column tube ( 32 );

b) lowering the bottom end cell ( 26 );

c) conducting maintenance to the bottom end cell ( 26 );

d) raising the bottom end cell ( 26 ) against the column tube ( 32 );

e) releasing the column tube ( 32 ) form the top end cell ( 20 );

lowering the bottom end cell ( 26 ) together with the column tube ( 32 );

g) rotating the top end cell ( 20 ) 180 degrees around a horizontal axis; and

h) conducting maintenance to the top end cell ( 20 ).

Assignments (2)
CHANGE OF NAME Recorded Oct 5, 2020
From: GE HEALTHCARE BIO-SCIENCES AB
To: CYTIVA SWEDEN AB
Reel/Frame 054262/0184 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 15, 2012
From: USELIUS, PER; DAMBULEFF, KYRIL; DAVIS, JOHN
To: GE HEALTHCARE BIO-SCIENCES AB
Reel/Frame 028790/0799 →