Method and apparatus for programmable fluidic processing
A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation force is applied to the packet at the position. The programmable manipulation force is adjustable according to packet position by a controller. The packet is programmably moved according to the programmable manipulation force along arbitrarily chosen paths.
1. An apparatus for programmably manipulating a packet, the apparatus comprising:
a fluidic device comprising a reaction surface and an array, the array comprising a plurality of elements that are individually addressable;
a signal generator configured to apply electrical signals to the elements to generate electrical field distributions and impart manipulation forces on a packet to programmably move the packet about the reaction surface; and
a controller coupled to the signal generator and configured to adjust the programmable manipulation forces, the controller further configured to be coupled to a screen to display a bitmap corresponding to the elements of the array and to adjust the programmable manipulation forces according to user modifications to the bitmap.
2. The apparatus of claim 1 , further comprising a switching network coupled to the signal generator and the controller.
3. The apparatus of claim 2 , further comprising a plurality of resistors coupled to the switching network and the signal generator to vary a voltage amplitude of the electrical signals applied to the elements.
4. The apparatus of claim 1 , further comprising:
a memory coupled to and accessible by the controller, the memory storing a plurality of subroutines for programmably manipulating a packet about the reaction surface.
5. The apparatus of claim 4 , further comprising:
a position sensor configured to detect a position of a packet on the reaction surface.
6. The apparatus of claim 5 , where the position sensor comprises a conductor configured to measure an electrical impedance of the packet.
7. The apparatus of claim 5 , where the position sensor comprises an optical system configured to monitor the position of the packet.
8. The apparatus of claim 1 , where the fluidic device comprises an integrated circuit that includes the elements of the array.
9. The apparatus of claim 1 , further comprising:
a display;
where the controller and display are included in a personal computing device.