IP Library › Granted Patent US 9,618,515
Granted Patent B2
US 9,618,515 · App. 13/554,623 · Granted Apr 11, 2017

Assay to capture and detect circulating multiple myeloma cells from blood

Inventors: Steven Gross (Ambler, PA); Mark Carle Connelly (Doylestown, PA); Galla Chandra Rao (Princeton Jct., NJ); Marielena Mata (Philadelphia, PA); Carrie Morano (Hamilton, NJ)
Assignee: Janssen Diagnostics, LLC
G01N33/57492B03C1/01B03C1/28G01N33/57426B03C2201/26
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Quick Facts
Patent No.
US 9,618,515
App. No.
13/554,623
Granted
Apr 11, 2017
Kind
B2
Abstract

The invention includes methods for isolating circulating multiple myeloma cells as well as method of treating patients suspected of having diseases of abnormal plasma cells.

Claims (2)

1. A reagent for capturing circulating multiple myeloma cells comprising colloidal magnetic particles and at least two ligands, wherein the ligands are selected from the group consisting of anti CD 138, anti-CD 38, and anti-CD56.

2. The reagent of claim 1 further comprising at least three ligands.

Assignments (3)
NUNC PRO TUNC ASSIGNMENT Recorded Jan 4, 2019
From: MENARINI SILICON BIOSYSTEMS, INC.
To: MENARINI SILICON BIOSYSTEMS S.P.A.
Reel/Frame 049631/0823 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 2, 2018
From: JANSSEN DIAGNOSTICS, LLC
To: MENARINI SILICON BIOSYSTEMS, INC.
Reel/Frame 045238/0050 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 20, 2014
From: GROSS, STEVEN; CONNELLY, MARK CARLE; RAO, GALLA CHANDRA; MATA, MARIELENA; MORANO, CARRIE
To: JANSSEN DIAGNOSTICS LLC
Reel/Frame 032480/0826 →
Continuity (2)
Provisional Application 61510170 · Jul 21, 2011
Related Publication 20130189675A1 · Jul 25, 2013