USE OF 1-HYDROXY-2- PYRIDONES FOR THE TREATMENT OF SEBORRHEIC DERMATITIS
Compounds of the formula (1) are disclosed and are suitable for the treatment of seborrheic dermatitis.
1 - 13 . (canceled)
14 . A solid pharmaceutical formulation comprising
One or more 1-hydroxy-2-pyridones selected from the group consisting of ciclopirox and octopirox; and
One or more surfactants.
15 . The formulation of claim 14 wherein the formulation has a pH of 4.5 to 6.5.
16 . The formulation of claim 14 wherein the 1-hydroxy-2-pyridone is ciclopirox.
17 . The formulation of claim 14 wherein the 1-hydroxy-2-pyridones are present in a concentration of 0.2% to 10% by weight of the formulation.
18 . The formulation of claim 14 wherein the 1-hydroxy-2-pyridones are present in a concentration of 0.5% to 2% by weight of the formulation.
19 . A method of treating seborrheic dermatitis comprising
Wetting and lathering a solid pharmaceutical formulation, wherein the formulation comprises one or more 1-hydroxy-2-pyridones selected from the group consisting of ciclopirox and octopirox; and one or more surfactants,
Applying the formulation to the skin, and
Washing off the formulation.
20 . The method of claim 19 wherein the formulation has a pH of 4.5 to 6.5.
21 . The method of claim 19 wherein the 1-hydroxy-2-pyridone is ciclopirox.
22 . The method of claim 19 wherein the 1-hydroxy-2-pyridones are present in a concentration of 0.2% to 10% by weight of the formulation.
23 . The method of claim 19 wherein the 1-hydroxy-2-pyridones are present in a concentration of 0.5% to 2% by weight of the formulation.