IP Library › Granted Patent US 8,653,286
Granted Patent B2
US 8,653,286 · App. 13/568,518 · Granted Feb 18, 2014

Intermediates useful in the preparation of maleimide functionalized polymers

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Quick Facts
Patent No.
US 8,653,286
App. No.
13/568,518
Granted
Feb 18, 2014
Kind
B2
Abstract

Methods for forming maleimide functionalized polymers are provided. In one such embodiment, a maleimide functionalized polymer is prepared in a method that includes a step of carrying out a reverse Diels-Alder reaction. Intermediates useful in the methods, as well as methods for preparing the intermediates, are also provided. Also provided are polymeric reagents, methods of using polymeric reagents, compounds and conjugates.

Claims (2)

1. A composition comprising (i) a compound of the following structure:

wherein n′ is 4 to about 10, and (ii) N,N-disuccinimidyl carbonate.

Assignments (4)
RELEASE OF SECURITY INTEREST Recorded Apr 17, 2020
From: TC LENDING, LLC, AS COLLATERAL AGENT
To: NEKTAR THERAPEUTICS
Reel/Frame 053180/0009 →
RELEASE OF SECURITY INTEREST RECORDED AT REEL 30040, FRAME 0952 Recorded Oct 14, 2015
From: WELLS FARGO BANK, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
To: NEKTAR THERAPEUTICS
Reel/Frame 036855/0793 →
GRANT OF SECURITY INTEREST IN UNITED STATES PATENTS Recorded Oct 6, 2015
From: NEKTAR THERAPEUTICS
To: TC LENDING, LLC, AS COLLATERAL AGENT
Reel/Frame 036796/0562 →
SECURITY AGREEMENT Recorded Mar 19, 2013
From: NEKTAR THERAPEUTICS
To: WELLS FARGO, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
Reel/Frame 030040/0952 →