Photostabilization of coenzyme Q compounds with alkoxycrylene compounds
View Patent ↗A method of reducing photodegradation of a coenzyme Q 10 compound when exposed to UV radiation in a composition containing said coenzyme Q 10 compound comprising combining with said coenzyme Q 10 compound a compound of formula (I) in an amount effective to quench singlet excited state energy from the coenzyme Q 10 compound and transfer the singlet excited state energy from the coenzyme Q 10 compound to the compound of formula (I), wherein one of R 1 and R 2 is a straight or branched chain C 1 -C 30 alkoxy radical, and the non-alkoxy R 1 or R 2 is hydrogen; and R 3 is a straight or branched chain C 1 -C 30 alkyl radical, thereby photostabilizing the retinoid compound.
1. A photostabilized sunscreen cosmetic or dermatological composition comprising a coenzyme Q 10 compound in an amount of about 0.001% to about 5% by weight and a compound of formula (I) in an amount of about 0.01% to about 20% by weight, based on the total weight of the composition, wherein the compound of formula (I) is
wherein one of R 1 and R 2 is a straight or branched chain C 1 -C 30 alkoxy radical, and the non-alkoxy R 1 or R 2 is hydrogen; and R 3 is a straight or branched chain C 1 -C 30 alkyl radical.
2. The photostabilized composition of claim 1 , wherein R 1 is methoxy and R 2 is hydrogen.
3. The photostabilized composition of claim 1 , wherein R 1 is hydrogen and R 2 is methoxy.
4. The photostabilized composition of claim 1 , wherein R 3 is a C 12 -C 24 straight chain or branched alkyl.
5. The photostabilized composition of claim 4 , wherein R 3 is a 2-butyloctyl radical.
6. The photostabilized composition of claim 4 , wherein R 3 is an 2-ethylhexyl radical.
7. The photostabilized composition of claim 1 , wherein the compound of formula (I) is present in an amount in the weight range of about 0.1% to about 20%, based on the total weight of the composition.
8. The photostabilized composition of claim 7 , wherein the compound of formula (I) is present in an amount in this weight range of about 0.1% to about 10%, based on the total weight of the composition.
9. The photostabilized composition of claim 1 , wherein the compound of formula (I) is present in an amount in this weight range of about 0.1% to about 5%, based on the total weight of the composition.
10. The photostabilized composition of claim 1 , wherein the coenzyme Q 10 compound is present in an amount in the weight range of about 0.01% to about 5%, based on the total weight of the composition.
11. The photostabilized composition of claim 10 , wherein the coenzyme Q 10 compound is present in this weight range of about 0.01% to about 1%, based on the total weight of the composition.
12. The photostabilized composition of claim 11 , wherein the coenzyme Q 10 compound is present in this weight range of about 0.01% to about 0.5%, based on the total weight of the composition.