Bioabsorbable mesh for surgical implants
View Patent ↗Described are methods, devices, and systems related to pelvic implants, including implants that include absorbable and non-absorbable materials.
1. An implantable mesh comprising
a plurality of non-absorbable fibers interwoven or knit to produce a porous mesh, and
absorbable polymer, where the absorbable polymer is (a) filled, intermittently or completely, in openings in the porous mesh, (b) applied at an intersection of non-absorbable fibers, or both (a) and (b),
wherein the absorbable polymer degrades after implantation into a human subject.
2. A mesh according to claim 1 wherein absorbable polymer is filled intermittently in openings in the porous mesh.
3. A method of treating a pelvic condition by supporting tissue of a pelvic region, the method comprising
providing an implant comprising the mesh of claim 1
wherein the absorbable polymer degrades after implantation into a human subject, and
implanting the implant in a patient to support tissue of a pelvic region.
4. A method according to claim 3 comprising
creating an incision that allows access to a region of tissue of the pelvic floor,
providing the implant, the implant comprising a tissue support portion and an elongate end portion,
passing the implant through the incision and placing the tissue support portion at the region of pelvic floor tissue,
placing the elongate end portion at a location to support the tissue support portion, and
positioning the tissue support portion at the region of the pelvic floor tissue in a manner to cause the tissue support portion to support the tissue of the pelvic floor tissue.
5. A method according to claim 4 wherein the tissue support portion the mesh comprising the non-absorbable fibers and absorbable polymer.
6. A method according to claim 4 wherein the elongate end portion the mesh comprising the non-absorbable fibers and absorbable polymer.
7. The method according to claim 3 wherein the method is selected from the group consisting of:
a method of treating male urinary incontinence,
a method of treating female urinary incontinence,
a method of treating fecal incontinence,
a method of supporting a perineal body,
a method of perineal body repair,
a method of treating levator avulsion,
a method of treating levator ballooning,
a method of supporting levator ani muscle,
a method of levator ani muscle repair,
a method of tightening or reducing the size of a levator hiatus,
a method of treating vaginal prolapse,
and combinations of one or more of these.
8. A method according to claim 3 wherein the implant comprises a tissue fastener, and the method comprises securing the tissue fastener to tissue of the pelvic region.
9. A method according to claim 8 comprising securing the implant to tissue selected from: sacrotuberous ligament, sacrospinous ligament, periostium of the pubic bone, pubourethral ligament, a region of the ischial spine, ischial tuberosity, tissue of an obturator foramen, and arcus tendineus.
10. The mesh according claim 1 wherein non-absorbable fibers comprise polypropylene.
11. The mesh according to claim 1 wherein absorbable polymer is selected from the group consisting of polyhydroxyalkanoate, poly-L-lactic acid, polyanhydride, polycaprolactone, polyglycolic acid, poly-L-lactic acid, poly-D-L-lactic acid, polydioxanone, polyphosphate ester, and combinations thereof.
12. A mesh according to claim 11 wherein absorbable polymer comprises polyhydroxyalkanoate.
13. The mesh according to claim 1 wherein the openings are completely filled with the absorbable polymer.
14. The mesh according to claim 1 wherein the fibers of the mesh have intersecting portions, and the absorbable material is placed at intersecting portions.
15. The mesh according to claim 14 wherein the absorbable material is placed at intersecting portions used as a hot-melt glue.
16. The mesh according to claim 14 wherein the absorbable material is placed at intersecting portions randomly or in a pattern.