INFILTRATION SOLUTION FOR TREATING AN ENAMEL LESION
The invention relates to an infiltration solution of a radiopaque metal compound for treating an enamel lesion, to a kit for dental application, and to the use thereof for preventing and/or treating (sealing) carious enamel lesions.
1 . An infiltration solution for treating an enamel lesion, comprising:
(a) at least 25% by weight of a solvent or solvent mixture which is volatile at room temperature (23° C.), and
(b) in solution in the solvent or solvent mixture, a radiopaque metal compound having a radiopacity of more than 200% aluminum as determined in accordance with EN ISO 4049:2000.
2 . The infiltration solution of claim 1 , wherein the infiltration solution at room temperature (23° C.) has a penetration coefficient PC of greater than 100 cm/s.
3 - 15 . (canceled)
16 . The infiltration solution of claim 1 , wherein said infiltration solution at room temperature (23° C.) has a penetration coefficient PC of greater than 200 cm/s.
17 . The infiltration solution of claim 1 , wherein said infiltration solution at room temperature (23° C.) has a penetration coefficient PC of greater than 300 cm/s.
18 . The infiltration solution of claim 1 , wherein said solvent or solvent mixture (a) has an evaporation index EI of less than 35 according to DIN 53170:2009.
19 . The infiltration solution of claim 1 , wherein said solvent or solvent mixture (a) has an evaporation index EI of less than 10 according to DIN 53170:2009.
20 . The infiltration solution of claim 1 , wherein said infiltration solution is composed to an extent of at least 80% by weight of the solvent or solvent mixture (a) and of the dissolved metal compound (b).
21 . The infiltration solution of claim 1 , wherein said infiltration solution is composed to an extent of at least 90% by weight of the solvent or solvent mixture (a) and of the dissolved metal compound (b).
22 . The infiltration solution of claim 1 , wherein said infiltration solution is composed to an extent of at least 95% by weight of the solvent or solvent mixture (a) and of the dissolved metal compound (b).
23 . The infiltration solution of claim 1 , wherein said solvent or solvent mixture (a) is selected from the group consisting of alcohols, ethers, ketones, and esters.
24 . The infiltration solution of claim 1 , wherein said infiltration solution comprises at least 30% by weight of the solvent or solvent mixture (a).
25 . The infiltration solution of claim 1 , wherein said infiltration solution comprises at least 35% to 70% by weight, of the solvent or solvent mixture (a).
26 . The infiltration solution of claim 1 , wherein said dissolved metal compound (b) has a radiopacity of greater than 300% aluminum.
27 . The infiltration solution of claim 1 , wherein said dissolved metal compound (b) has a radiopacity of greater than 500% aluminum.
28 . The infiltration solution of claim 1 , wherein said dissolved metal compound (b) has a radiopacity of greater than 700% aluminum.
29 . The infiltration solution of claim 1 , wherein said dissolved metal compound (b) is the compound of a metal with an atomic number of 30 or higher.
30 . The infiltration solution of claim 1 , wherein said dissolved metal compound (b) is the compound of a metal with an atomic number of 38 to 83.
31 . The infiltration solution of claim 1 , wherein said dissolved metal compound (b) is a salt.
32 . The infiltration solution of claim 1 , wherein said dissolved metal compound is an organometallic compound.
33 . The infiltration solution of claim 1 , wherein said infiltration solution comprises at least 5% by weight of the dissolved metal compound.
34 . The infiltration solution of claim 1 , wherein said infiltration solution comprises at least 20% by weight of the dissolved metal compound.
35 . The infiltration solution of claim 1 , wherein said infiltration solution comprises at least 25% by weight of the dissolved metal compound.
36 . The infiltration solution of claim 1 , wherein said infiltration solution comprises at least 30 to 65% by weight of the dissolved metal compound.
37 . The infiltration solution of claim 1 , wherein said infiltration solution comprises the dissolved metal compound in colloidal solution.
38 . The infiltration solution of claim 1 , wherein said infiltration solution comprises the dissolved metal compound in true solution.
39 . A kit for treating an enamel lesion, comprising the infiltration solution of claim 1 and a curable infiltrant.
40 . The kit claim 39 , wherein said enamel lesion is a carious enamel lesion.