Matrices and media for storage and stabilization of biomolecules
View Patent ↗The present invention provides compositions useful for biomolecule storage comprising a water soluble inorganic compound, a stabilizer, or a combination thereof. The present invention also provides methods of using the compositions of the invention to store biomolecules in the dry state and in solution, as well as sample carriers and kits comprising compositions of the invention.
1. A composition comprising:
boric acid or a salt thereof;
a plasticizer, wherein the plasticizer is a poly-alcohol;
a hydroxyl radical scavenger; and
an RNase inhibitor, wherein the RNase inhibitor is aluminon,
wherein the composition is:
a solid-state or dry-state matrix in a solid or dry form which can be converted to a liquid form by suspending, re-hydrating, or solubilizing the matrix in water; or
an aqueous medium in a liquid state.
2. The composition of claim 1 , further comprising a metal chelater.
3. The composition of claim 2 wherein the metal chelater is EDTA.
4. The composition of claim 1 wherein the hydroxyl radical scavenger is histidine.