ORAL ANTIMICROBIAL PHARMACEUTICAL COMPOSITIONS
The present invention relates to oral pharmaceutical compositions with controlled and/or programmed release containing at least one active ingredient having antimicrobial and/or anti-infectious activity for the treatment of infections of the large intestine, in particular the colon.
1 . A controlled release oral pharmaceutical composition comprising:
(1) rifamycin SV in an amount effective for treatment of infections of the large intestine, and (2) means for delivering said effective amount of rifamycin SV substantially in the large intestine.
2 . A controlled release oral pharmaceutical composition according to claim 1 , wherein said delivery of said rifamycin SV is substantially in the colon.
3 . A method of treating intestinal infections in a patient in need thereof, comprising administering to said patient a controlled release oral pharmaceutical composition according to claim 1 .
4 . A method of treating intestinal infections in a patient in need thereof, comprising administering to said patient a controlled release oral pharmaceutical composition according to claim 2 .